Refreshing Vitamin Tea™ 50g

£7.00

T’n’T Teas’® Refreshing Vitamin™ tea is the perfect blend that transforms your daily ritual into a fruity, tangy, and harmonious experience. Sip, smile, and let the vibrant flavours and healthful benefits transport you to a rejuvenating paradise.

Out of stock

Description

Embark on a delightful flavour journey with T’n’T Teas’® Refreshing Vitamin™ tea blend. It’s a harmonious infusion that will tantalise your taste buds, offering a symphony of tastes to savour. Sip your way to serenity as you experience the intricate balance of nature’s finest elements. Uncover a cup of pure well-being, crafted with dedication and expertise.

The Refreshing Vitamin™ tea is a refreshing blend of hibiscus, lavender, rosehips, spearmint, and nettle. This delightful concoction offers a burst of fruity and floral notes, paired with healthful goodness.

The adventure begins with the tangy embrace of hibiscus, like a burst of tropical flavour, followed by the calming influence of lavender, akin to a tranquil meadow. Rosehips contribute a zesty and tangy note, like a symphony of citrus, while spearmint adds a refreshing kick. Nettle joins the party, creating a harmonious herbal ensemble that’s like a nature hike for your taste buds.

Please use the button below to download the Wellbeing Factsheet that provides you with the benefits, side effects, contradictions and clinical/traditional evidence.

Factsheet button

We offer discounts if you buy more than 1. Buy 2 teas for £12, and 3 for £15 (additional teas charged at £5 each).

Additional information

Weight50 g

Wellbeing / Side Effects

This blend is not only a delight to your palate but also a healthful hug for your body. Hibiscus is known for its antioxidant properties, while rosehips offer a vitamin C boost. Lavender promotes relaxation and balance, and spearmint aids digestion. Nettle provides essential vitamins and minerals, making this a well-rounded vitamin infusion.

The Refreshing Vitamin Mint™ Tea is a 100% natural product, it does not contain allergens or impurities, and it does not contain added flavours, so its consumption should not cause unpleasant stomach upsets.

T’n’T Teas® Refreshing Vitamin Mint™ Tea is a certified, premium quality professionally mixed product, made with the highest quality, medicinal natural herbs from around the world. We pay special attention to the purity of the plants, so we only buy the certified raw materials for our products from reliable, controlled sources, so we can ensure that we minimise contact with foreign substances during storage, transportation, and production.

This tea blend is generally well-tolerated, but there are a few potential side effects to be aware of:
Hibiscus: Hibiscus may interact with certain medications, such as blood pressure medications (lowering blood pressure) and diuretics. Additionally, pregnant and breastfeeding women should talk to their doctor before consuming hibiscus.

Lavender: Lavender may interact with certain medications, such as sedatives and anxiety medications. Additionally, pregnant and breastfeeding women should talk to their doctor before consuming lavender.

Rosehips: Rosehips may interact with certain medications, such as blood thinners and diuretics. Additionally, pregnant and breastfeeding women should talk to their doctor before consuming rosehips.

Spearmint: Spearmint may interact with certain medications, such as blood pressure medications (increasing blood pressure) and diuretics. Additionally, pregnant and breastfeeding women should talk to their doctor before consuming spearmint.

Nettle: Nettle may interact with diuretics and lithium. Additionally, pregnant and breastfeeding women should talk to their doctor before consuming nettle.

Allergens:
This tea blend is naturally free of common allergens, but it is always important to check the ingredient list for specific concerns.

Contraindications
Avoid this tea blend if you have known allergies to any of the listed ingredients. Consult your healthcare provider if pregnant, nursing, or with specific health conditions. Not suitable for children under 12 years.

For legal reasons, we are prohibited from advertising the well-being benefits or possible side effects of this tea. Please contact us for a free consultation for more information.

CAUTION: Herbs have medicinal properties and can promote the body’s physical and mental self-healing and harmonising process, but they cannot replace medical examination, care and possible treatment – so if you are on medication from your doctor, please check that they are happy for you to drink the tea. If you feel any discomfort, stop and only restart slowly if you are comfortable doing so (it might not be the herbal tea that causes the discomfort!). Pregnant or breastfeeding women, or children under the age of 12 years old, should exercise extra caution.

For a detailed description, please look at the individual ingredients.

Profile

Colour: A vibrant, sunset-inspired infusion that’s as lively as a tropical paradise.
Aroma: It’s a playful fiesta of fruity and floral notes, like an enticing luau in your cup.
Initial taste: The first sip is like a splash of sunshine, with tangy hibiscus and zesty rosehips taking center stage.
Midtones: Lavender adds a touch of tranquility, and spearmint brings a refreshing twist, like a tropical breeze.
Aftertaste: A hint of serenity lingers, like the soothing sound of ocean waves, leaving you refreshed.
Body: It’s a light and invigorating dance on your palate, like a beachside stroll on a sunny day.
Caffeine content: This tea blend is caffeine-free, ensuring a serene and playful sip without any jitters.

Ingredients

HibiscusHibiscus

RosehipsRosehips

LavenderLavender

SpearmintSpearmint

NettleNettle

Cruelty-free logoGMO-Free. Suitable for vegans.

Warning: Prepared in an area where Mustard seed & Celery are also used. Herbs have medicinal properties that will affect the body but should not replace examination and advice from your medical practitioner. Please check that they are happy for you to drink herbal infusions. If you feel any discomfort, stop immediately and find out the cause (it may not be herbal tea that caused the discomfort!).

This tea contains 100% natural products without allergens or impurities, and no added flavours or colourants, so its consumption should not cause any unpleasant stomach upsets. Please refer to possible side effects on this website.

Certified Origins

Bulgarian flag Egyptian flag Hungarian flag denoting that one or more ingredient was ethically sourced from Hungary.Nigerian flag denoting that one or more ingredient was ethicall sourced from Nigeria..

Hand-blended in Shropshire, England.

Preparation

“Brewing Paradise!” – Preparation notes for T’n’T Teas’® Refreshing Vitamin™ tea blend:

  1. Tropical vibes: Get into the spirit! Grab your favourite cup or teapot, and let’s embark on a flavour-filled adventure.
  2. Fruity fiesta: Scoop a teaspoon of our Refreshing Vitamin™ tea blend. Hibiscus, lavender, rosehips, spearmint, and nettle are ready to party.
  3. Sunshine brew: Heat fresh, cold water to around 96°C (205°F). We’re creating a tropical paradise here!
  4. Luau steeping: Pour the hot water over the tea blend, like a waterfall cascading into a lagoon. Let them steep for 10-15 minutes.
  5. Aloha lid: Cover your cup or teapot with a lid while the herbs and spices create their luau magic.
  6. Tropical twist: If you like, add a slice of pineapple or a squeeze of lime. It’s your personal luau touch to the fiesta.
  7. Strain and sip: The tropical show’s about to begin! Strain the tea blend, and let the luau commence.
  8. Sip and smile: Hold your cup close and sip the fruity and floral flavors. It’s like attending a beachside party with friends.
  9. Encore anytime: The fiesta doesn’t have to end after one act. Feel free to steep another round and keep the luau going.
  10. Island bliss: Store your tea blend in a cool, dry place, ready for the next tropical adventure.

Get ready to sip and savour the playful flavours of T’n’T Teas’® Refreshing Vitamin™ tea blend. Let the luau of fruity and floral goodness begin!

For the best flavour, store in a cool dark place.

Clinical References

Clinical evidence of the ingredients found in this product. These are public domain references and do not relate directly to our product.

Hibiscus

  • Abubakar SM, Ukeyima MT, Spencer JPE, Lovegrove JA. Acute effects of Hibiscus sabdariffa calyces on postprandial blood pressure, vascular function, blood lipids, biomarkers of insulin resistance and inflammation in humans. Nutrients. 2019;11(2). pii: E341.
  • Ahad A, Raish M, Bin Jardan YA, Alam MA, Al-Mohizea AM, Al-Jenoobi FI. Effect of Hibiscus sabdariffa and Zingiber officinale on the antihypertensive activity and pharmacokinetic of losartan in hypertensive rats. Xenobiotica. 2020:1-11.
  • Al-Anbaki M, Cavin AL, Nogueira RC, et al. Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention. Plants (Basel) 2021;10(5):1018.
  • Al-Anbaki M, Nogueira RC, Cavin AL, et al. Treating uncontrolled hypertension with Hibiscus sabdariffa when standard treatment is insufficient: Pilot intervention. J Altern Complement Med. 2019;25(12):1200-1205.
  • Alam MA, Bin Jardan YA, Alzenaidy B, et al. Effect of Hibiscus sabdariffa and Zingiber officinale on pharmacokinetics and pharmacodynamics of amlodipine. J Pharm Pharmacol 2021;73(9):1151-60.
  • Alarcón-Alonso J, Zamilpa A, Aguilar FA, Herrera-Ruiz M, Tortoriello J, Jimenez-Ferrer E. Pharmacological characterization of the diuretic effect of Hibiscus sabdariffa Linn (Malvaceae) extract. J Ethnopharmacol. 2012 Feb 15;139(3):751-6.
  • Ali, B. H., Al, Wabel N., and Blunden, G. Phytochemical, pharmacological and toxicological aspects of Hibiscus sabdariffa L.: a review. Phytother.Res 2005;19(5):369-375.
  • Asgary S, Soltani R, Zolghadr M, Keshvari M, Sarrafzadegan N. Evaluation of the effects of roselle (Hibiscus sabdariffa L.) on oxidative stress and serum levels of lipids, insulin and hs-CRP in adult patients with metabolic syndrome: a double-blind placebo-controlled clinical trial. J Complement Integr Med. 2016;13(2):175-80.
  • Aziz Z, Wong SY, Chong NJ. Effects of Hibiscus sabdariffa L. on serum lipids: a systematic review and meta-analysis. J Ethnopharmacol. 2013 Nov 25;150(2):442-50.
  • Baranova, V. S., Rusina, I. F., Guseva, D. A., Prozorovskaia, N. N., Ipatova, O. M., and Kasaikina, O. T. [The antiradical activity of plant extracts and healthful preventive combinations of these exrtacts with the phospholipid complex]. Biomed.Khim. 2012;58(6):712-726.
  • Barletta C, Paccone M, Uccello N, et al. Efficacy of food supplement Acidif plus in the treatment of uncomplicated UTIs in women: a pilot observational study. Minerva Ginecol. 2020;72(2):70-74.
  • Boix-Castejón M, Herranz-López M, Pérez Gago A, et al. Hibiscus and lemon verbena polyphenols modulate appetite-related biomarkers in overweight subjects: a randomized controlled trial. Food Funct. 2018;9(6):3173-3184.
  • Builders PF, Kabele-Toge B, Builders M, Chindo BA, Anwunobi PA, Isimi YC. Wound healing potential of formulated extract from hibiscus sabdariffa calyx. Indian J Pharm Sci. 2013 Jan;75(1):45-52.
  • Bule M, Albelbeisi AH, Nikfar S, Amini M, Abdollahi M. The antidiabetic and antilipidemic effects of Hibiscus sabdariffa: A systematic review and meta-analysis of randomized clinical trials. Food Res Int. 2020;130:108980.
  • Cai T, Tamanini I, Cocci A, et al. Xyloglucan, hibiscus and propolis to reduce symptoms and antibiotics use in recurrent UTIs: a prospective study. Future Microbiol. 2019;14:1013-1021.
  • Chou ST, Lo HY, Li CC, Cheng LC, Chou PC, Lee YC, Ho TY, Hsiang CY. Exploring the effect and mechanism of Hibiscus sabdariffa on urinary tract infection and experimental renal inflammation. J Ethnopharmacol. 2016 Dec 24;194:617-625.
  • Da-Costa-Rocha I, Bonnlaender B, Sievers H, Pischel I, Heinrich M. Hibiscus sabdariffa L. – a phytochemical and pharmacological review. Food Chem. 2014 Dec 15;165:424-43.
  • Diantini A, Rahmat S, Alpiani A, Sumiwi SA, Lubis L, Levita J. Effect of the roselle (Hibiscus sabdariffa L.) calyces drink on the physiological parameters of healthy adult subjects. Biomed Rep 2021;15(5):89.
  • El Basheir, Z. M. and Fouad, M. A. A preliminary pilot survey on head lice, pediculosis in Sharkia Governorate and treatment of lice with natural plant extracts. J.Egypt.Soc.Parasitol. 2002;32(3):725-736.
  • Electronic Code of Federal Regulations. Title 21. Part 182 — Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  • Elkafrawy N, Younes K, Naguib A, et al. Antihypertensive efficacy and safety of a standardized herbal medicinal product of Hibiscus sabdariffa and Olea europaea extracts (NW Roselle): A phase-II, randomized, double-blind, captopril-controlled clinical trial. Phytother Res. 2020;34(12):3379-3387.
  • Fakeye TO, Adegoke AO, Omoyeni OC, Famakinde AA. Effects of water extract of Hibiscus sabdariffa, Linn (Malvaceae) ‘Roselle’ on excretion of a diclofenac formulation. Phytother Res. 2007;21(1):96-8.
  • Frank, T., Janssen, M., Netzel, M., Strass, G., Kler, A., Kriesl, E., and Bitsch, I. Pharmacokinetics of anthocyanidin-3-glycosides following consumption of Hibiscus sabdariffa L. extract. J Clin Pharmacol 2005;45(2):203-210.
  • Frank, T., Netzel, G., Kammerer, D. R., Carle, R., Kler, A., Kriesl, E., Bitsch, I., Bitsch, R., and Netzel, M. Consumption of Hibiscus sabdariffa L. aqueous extract and its impact on systemic antioxidant potential in healthy subjects. J Sci Food Agric. 8-15-2012;92(10):2207-2218.
  • Gurrola-Diaz, C. M., Garcia-Lopez, P. M., Sanchez-Enriquez, S., Troyo-Sanroman, R., Andrade-Gonzalez, I., and Gomez-Leyva, J. F. Effects of Hibiscus sabdariffa extract powder and preventive treatment (diet) on the lipid profiles of patients with metabolic syndrome (MeSy). Phytomedicine. 2010;17(7):500-505.
  • Hadi A, Pourmasoumi M, Kafeshani M, Karimian J, Maracy MR, Entezari MH. The Effect of Green Tea and Sour Tea (Hibiscus sabdariffa L.) Supplementation on Oxidative Stress and Muscle Damage in Athletes. J Diet Suppl. 2017 May 4;14(3):346-357.
  • Haji, Faraji M. and Haji, Tarkhani A. The effect of sour tea (Hibiscus sabdariffa) on essential hypertension. J.Ethnopharmacol. 1999;65(3):231-236.
  • Hernandez-Perez, F. and Herrera-Arellano, A. [Therapeutic use Hibiscus sabadariffa extract in the treatment of hypercholesterolemia. A randomized clinical trial]. Rev.Med Inst.Mex.Seguro.Soc. 2011;49(5):469-480.
  • Herranz-López M, Olivares-Vicente M, Boix-Castejón M, Caturla N, Roche E, Micol V. Differential effects of a combination of Hibiscus sabdariffa and Lippia citriodora polyphenols in overweight/obese subjects: A randomized controlled trial. Sci Rep. 2019;9(1):2999.
  • Herrera-Arellano, A., Flores-Romero, S., Chavez-Soto, M. A., and Tortoriello, J. Effectiveness and tolerability of a standardized extract from Hibiscus sabdariffa in patients with mild to moderate hypertension: a controlled and randomized clinical trial. Phytomedicine. 2004;11(5):375-382.
  • Herrera-Arellano, A., Miranda-Sanchez, J., Avila-Castro, P., Herrera-Alvarez, S., Jimenez-Ferrer, J. E., Zamilpa, A., Roman-Ramos, R., Ponce-Monter, H., and Tortoriello, J. Clinical effects produced by a standardized herbal medicinal product of Hibiscus sabdariffa on patients with hypertension. A randomized, double-blind, lisinopril-controlled clinical trial. Planta Med 2007;73(1):6-12.
  • Iyare EE, Adegoke OA. Maternal consumption of an aqueous extract of Hibiscus sabdariffa during lactation accelerates postnatal weight and delays onset of puberty in female offspring. Niger J Physiol Sci. 2008 Jun-Dec;23(1-2):89-94.
  • Jalalyazdi M, Ramezani J, Izadi-Moud A, Madani-Sani F, Shahlaei S, Ghiasi SS. Effect of hibiscus sabdariffa on blood pressure in patients with stage 1 hypertension. J Adv Pharm Technol Res. 2019;10(3):107-111.
  • Johnson SS, Oyelola FT, Ari T, Juho H. In vitro inhibitory activities of the extract of Hibiscus sabdariffa L. (family Malvaceae) on selected cytochrome P450 isoforms. Afr J Tradit Complement Altern Med. 2013 Apr 12;10(3):533-40.
  • Kolawole JA, Maduenyi A. Effect of zobo drink (Hibiscus sabdariffa water extract) on pharmacokinetics of acetaminophen in human volunteers. Eur J Drug Metab Pharmacokinet 2004;29:25-9.
  • Kuriyan R, Kumar DR, Rajendran R, Kurpad AV. An evaluation of the hypolipidemic effect of an extract of Hibiscus Sabdariffa leaves in hyperlipidemic Indians: a double blind, placebo controlled trial. BMC Complement Altern Med 2010;10:27.
  • Lee CH, Kuo CY, Wang CJ, Wang CP, Lee YR, Hung CN, Lee HJ. A polyphenol extract of Hibiscus sabdariffa L. ameliorates acetaminophen-induced hepatic steatosis by attenuating the mitochondrial dysfunction in vivo and in vitro. Biosci Biotechnol Biochem. 2012;76(4):646-51.
  • Levrini L, Azzi L, Bossi S. The efficacy of a dietary supplement with carnosine and Hibiscus sabdariffa L. (AqualiefTM) in patients with xerostomia: a randomized, placebo-controlled, double-blind trial. Clin Ter 2020;171(4):e295-e301.
  • Mahmoud, B. M., Ali, H. M., Homeida, M. M., and Bennett, J. L. Significant reduction in chloroquine bioavailability following coadministration with the Sudanese beverages Aradaib, Karkadi and Lemon. J.Antimicrob.Chemother. 1994;33(5):1005-1009.
  • Marhuenda J, Pérez-Piñero S, Arcusa R, et al. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of a polyphenolic extract (Hibiscus sabdariffa and Lippia citriodora) for reducing blood pressure in prehypertensive and type 1 hypertensive subjects. Molecules. 2021;26(6):1783.
  • McKay DL, Chen CY, Saltzman E, Blumberg JB. Hibiscus Sabdariffa L. tea (tisane) lowers blood pressure in prehypertensive and mildly hypertensive adults. J Nutr 2010;140:298-303.
  • Micucci M, Angeletti A, Cont M, Corazza I, Aldini R, Donadio E, Chiarini A, Budriesi R. Hibiscus Sabdariffa L. Flowers and Olea Europea L. Leaves Extract-Based Formulation for Hypertension Care: In Vitro Efficacy and Toxicological Profile. J Med Food. 2016 May;19(5):504-12.
  • Milandri R, Maltagliati M, Bocchialini T, et al. Effectiveness of D-mannose, Hibiscus sabdariffa and Lactobacillus plantarum therapy in prevention of infectious events following urodynamic study. Urologia. 2019;86(3):122-125.
  • Mohagheghi A, Maghsoud S, Khashayar P, Ghazi-Khansari M. The effect of hibiscus sabdariffa on lipid profile, creatinine, and serum electrolytes: a randomized clinical trial. ISRN Gastroenterol. 2011;2011:976019.
  • Mohamed R, Fernandez J, Pineda M, Aguilar M. Roselle (Hibiscus sabdariffa) seed oil Is a rich source of gamma-tocopherol. J Food Sci 2007;72:S207-11.
  • Mozaffari-Khosravi H, Ahadi Z, Barzegar K. The effect of green tea and sour tea on blood pressure of patients with type 2 diabetes: a randomized clinical trial. J Diet Suppl. 2013 Jun;10(2):105-15.
  • Mozaffari-Khosravi, H., Jalali-Khanabadi, B. A., Afkhami-Ardekani, M., and Fatehi, F. Effects of sour tea (Hibiscus sabdariffa) on lipid profile and lipoproteins in patients with type II diabetes. J Altern.Complement Med 2009;15(8):899-903.
  • Mozaffari-Khosravi, H., Jalali-Khanabadi, B. A., Afkhami-Ardekani, M., Fatehi, F., and Noori-Shadkam, M. The effects of sour tea (Hibiscus sabdariffa) on hypertension in patients with type II diabetes. J Hum.Hypertens 2009;23(1):48-54.
  • Najafpour Boushehri S, Karimbeiki R, Ghasempour S, et al. The efficacy of sour tea (Hibiscus sabdariffa L.) on selected cardiovascular disease risk factors: A systematic review and meta-analysis of randomized clinical trials. Phytother Res. 2020;34(2):329-339.
  • Ngamjarus C, Pattanittum P, Somboonporn C. Roselle for hypertension in adults. Cochrane Database Syst Rev 2010:1:CD007894.
  • Nwachukwu DC, Aneke E, Nwachukwu NZ, Obika LF, Nwagha UI, Eze AA. Effect of Hibiscus sabdariffaon blood pressure and electrolyte profile of mild to moderate hypertensive Nigerians: A comparative study with hydrochlorothiazide. Niger J Clin Pract. 2015 Nov-Dec;18(6):762-70.
  • Sabzghabaee AM, Ataei E, Kelishadi R, Ghannadi A, Soltani R, Badri S, Shirani S. Effect of Hibiscus sabdariffa Calices on Dyslipidemia in Obese Adolescents: A Triple-masked Randomized Controlled Trial. Mater Sociomed. 2013;25(2):76-9.
  • Serban C, Sahebkar A, Ursoniu S, Andrica F, Banach M. Effect of sour tea (Hibiscus sabdariffa L.) on arterial hypertension: a systematic review and meta-analysis of randomized controlled trials. J Hypertens. 2015 Jun;33(6):1119-27.
  • Showande SJ, Adegbolagun OM, Igbinoba SI, Fakeye TO. In vivo pharmacodynamic and pharmacokinetic interactions of Hibiscus sabdariffa calyces extracts with simvastatin. J Clin Pharm Ther. 2017;42(6):695-703.
  • Souirti Z, Loukili M, Soudy ID, et al. Hibiscus sabdariffa increases hydroxocobalamin oral bioavailability and clinical efficacy in vitamin B(12) deficiency with neurological symptoms. Fundam Clin Pharmacol. 2016;30(6):568-576.
  • Wahabi, H. A., Alansary, L. A., Al-Sabban, A. H., and Glasziuo, P. The effectiveness of Hibiscus sabdariffa in the treatment of hypertension: a systematic review. Phytomedicine. 2010;17(2):83-86.
  • Zhang B, Yue R, Wang Y, et al. Effect of Hibiscus sabdariffa (Roselle) supplementation in regulating blood lipids among patients with metabolic syndrome and related disorders: A systematic review and meta-analysis. Phytother Res. 2020;34(5):1083-1095.

Lavender

  • Abbasijahromi A, Hojati H, Nikooei S, et al. Compare the effect of aromatherapy using lavender and Damask rose essential oils on the level of anxiety and severity of pain following C-section: A double-blinded randomized clinical trial. J Complement Integr Med. 2019.
  • Abdelhakim AM, Hussein AS, Doheim MF, Sayed AK. The effect of inhalation aromatherapy in patients undergoing cardiac surgery: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med. 2020;48:102256.
  • Ahmad R, Naqvi AA, Al-Bukhaytan HM, Al-Nasser AH, Baqer Al-Ebrahim AH. Evaluation of aromatherapy with lavender oil on academic stress: A randomized placebo controlled clinical trial. Contemp Clin Trials Commun. 2019;14:100346.
  • Akhondzadeh S, Kashani L, Fotouhi A, et al. Comparison of Lavandula angustifolia Mill. tincture and imipramine in the treatment of mild to moderate depression: a double-blind, randomized trial. Prog Neuropsychopharmacol Biol Psychiatry 2003;27:123-7.
  • Altaei, D. T. Topical lavender oil for the treatment of recurrent aphthous ulceration. Am J Dent 2012;25(1):39-43.
  • Amirhosseini M, Dehghan M, Mangolian Shahrbabaki P, Pakmanesh H. Effectiveness of aromatherapy for relief of pain, nausea, and vomiting after percutaneous nephrolithotomy: a randomized controlled trial. Complement Med Res 2020:1-9.
  • Anderson C, Lis-Balchin M, Kirk-Smith M. Evaluation of massage with essential oils on childhood atopic eczema. Phytother Res 2000;14(6):452-6.
  • Apay, S. E., Arslan, S., Akpinar, R. B., and Celebioglu, A. Effect of aromatherapy massage on dysmenorrhea in Turkish students. Pain Manag.Nurs. 2012;13(4):236-240.
  • Araj-Khodaei M, Noorbala AA, Yarani R, et al. A double-blind, randomized pilot study for comparison of Melissa officinalis L. and Lavandula angustifolia Mill. with Fluoxetine for the treatment of depression. BMC Complement Med Ther. 2020;20(1):207.
  • Ardahan Akgül E, Karakul A, Altin A, Dogan P, Hosgör M, Oral A. Effectiveness of lavender inhalation aromatherapy on pain level and vital signs in children with burns: a randomized controlled trial. Complement Ther Med 2021;60:102758.
  • Arslan I, Aydinoglu S, Karan NB. Can lavender oil inhalation help to overcome dental anxiety and pain in children? A randomized clinical trial. Eur J Pediatr. 2020;179(6):985-992.
  • Bagheri-Nesami M, Espahbodi F, Nikkhah A, Shorofi SA, Charati JY. The effects of lavender aromatherapy on pain following needle insertion into a fistula in hemodialysis patients. Complement Ther Clin Pract. 2014;20(1):1-4.
  • Bagheri-Nesami M, Shorofi SA, Nikkhah A, Espahbodi F, Ghaderi Koolaee FS. The effects of aromatherapy with lavender essential oil on fatigue levels in haemodialysis patients: a randomized clinical trial. Complement Ther Clin Pract. 2016 Feb;22:33-7.
  • Bakhtiari S, Paki S, Khalili A, et al. Effect of lavender aromatherapy through inhalation on quality of life among postmenopausal women covered by a governmental health center in Isfahan, Iran: A single-blind clinical trial. Complement Ther Clin Pract 2019;34:46-50. doi: 10.1016/j.ctcp.2018.11.001.
  • Barker SC and Altman PM. A randomised, assessor blind, parallel group comparative efficacy trial of three products for the treatment of head lice in children–melaleuca oil and lavender oil, pyrethrins and piperonyl butoxide, and a “suffocation” product. BMC Dermatol 2010;10:6.
  • Barker SC and Altman PM. An ex vivo, assessor blind, randomised, parallel group, comparative efficacy trial of the ovicidal activity of three pediculicides after a single application–melaleuca oil and lavender oil, eucalyptus oil and lemon tea tree oil, and a “suffocation” pediculicide. BMC Dermatol 2011;11:14.
  • Bazrafshan MR, Jokar M, Shokrpour N, Delam H. The effect of lavender herbal tea on the anxiety and depression of the elderly: A randomized clinical trial. Complement Ther Med. 2020;50:102393.
  • Beyliklioglu A, Arslan S. Effect of lavender oil on the anxiety of patients before breast surgery. J Perianesth Nurs. 2019;34(3):587-593.
  • Bikmoradi A, Seifi Z, Poorolajal J, et al. Effect of inhalation aromatherapy with lavender essential oil on stress and vital signs in patients undergoing coronary artery bypass surgery: A single-blinded randomized clinical trial. Complement Ther Med. 2015;23(3):331-8.
  • Bingham LJ, Tam MM, Palmer AM, Cahill JL, Nixon RL. Contact allergy and allergic contact dermatitis caused by lavender: A retrospective study from an Australian clinic. Contact Dermatitis. 2019;81(1):37-42.
  • Braden, R., Reichow, S., and Halm, M. A. The use of the essential oil lavandin to reduce preoperative anxiety in surgical patients. J Perianesth.Nurs. 2009;24(6):348-355.
  • Bradley, B. F., Brown, S. L., Chu, S., and Lea, R. W. Effects of orally administered lavender essential oil on responses to anxiety-provoking film clips. Hum.Psychopharmacol. 2009;24(4):319-330.
  • Brandao FM. Occupational allergy to lavender oil. Contact Dermatitis 1986;15(4):249-250.
  • Buckle J. Aromatherapy. NursTimes 5-19-1993;89(20):32-35.
  • Buckle J. Use of aromatherapy as a complementary treatment for chronic pain. Altern Ther Health Med 1999;5:42-51.
  • Burke YD, Stark MJ, Roach SL, and et al. Inhibition of pancreatic cancer growth by the dietary isoprenoids farnesol and geraniol. Lipids 1997;32(2):151-156.
  • Cassella JP, Cassella S, Ashford R, and Siddals E. Antifungal activity of tea tree and lavender essential oils in the treatment of Trichophyton rubrum infection. Focus on Alternative and Complementary Therapies 2001;6(1):74.
  • Cetinkaya, B. and Basbakkal, Z. The effectiveness of aromatherapy massage using lavender oil as a treatment for infantile colic. Int J Nurs.Pract. 2012;18(2):164-169.
  • Cha, J. H., Lee, S. H., and Yoo, Y. S. [Effects of aromatherapy on changes in the autonomic nervous system, aortic pulse wave velocity and aortic augmentation index in patients with essential hypertension]. J Korean Acad Nurs. 2010;40(5):705-713.
  • Chang, S. Y. [Effects of aroma hand massage on pain, state anxiety and depression in hospice patients with terminal cancer]. Taehan Kanho.Hakhoe.Chi 2008;38(4):493-502.
  • Cheraghbeigi N, Modarresi M, Rezaei M, Khatony A. Comparing the effects of massage and aromatherapy massage with lavender oil on sleep quality of cardiac patients: A randomized controlled trial. Complement Ther Clin Pract. 2019;35:253-258.
  • Chung, M. and Choi, E. [A comparison between effects of aroma massage and meridian massage on constipation and stress in women college students]. J Korean Acad Nurs. 2011;41(1):26-35.
  • Clegg, R. J., Middleton, B., Bell, G. D., and White, D. A. The mechanism of cyclic monoterpene inhibition of hepatic 3-hydroxy-3- methylglutaryl coenzyme A reductase in vivo in the rat. J Biol Chem 3-10-1982;257(5):2294-2299.
  • Conrad, P. and Adams, C. The effects of clinical aromatherapy for anxiety and depression in the high risk postpartum woman – a pilot study. Complement Ther Clin Pract. 2012;18(3):164-168.
  • Cornwell S and Dale A. Lavender oil and perineal repair. Mod Midwife 1995;5(3):31-33.
  • Coulson IH and Khan AS. Facial ‘pillow’ dermatitis due to lavender oil allergy. Contact Dermatitis 1999;41(2):111.
  • D’Auria, F. D., Tecca, M., Strippoli, V., Salvatore, G., Battinelli, L., and Mazzanti, G. Antifungal activity of Lavandula angustifolia essential oil against Candida albicans yeast and mycelial form. Med Mycol. 2005;43(5):391-396.
  • Dale A, Cornwell S. The role of lavender oil in relieving perineal discomfort following childbirth: a blind randomized clinical trial. J Adv Nurs 1994;19(1):89-96.
  • Davari H, Ebrahimian A, Rezayei S, Tourdeh M. Effect of lavender aromatherapy on sleep quality and physiological indicators in patients after CABG surgery: A clinical trial study. Indian J Crit Care Med 2021;25(4):429-434.
  • Diaz A, Luque L, Badar Z, Kornic S, Danon M. Prepubertal gynecomastia and chronic lavender exposure: report of three cases. J Pediatr Endocrinol Metab. 2016 Jan;29(1):103-7.
  • Diego MA, Jones NA, Field T, and et al. Aromatherapy positively affects mood, EEG patterns of alertness and math computations. Int J Neurosci. 1998;96(3-4):217-224.
  • Djenane, D., Aider, M., Yanguela, J., Idir, L., Gomez, D., and Roncales, P. Antioxidant and antibacterial effects of Lavandula and Mentha essential oils in minced beef inoculated with E. coli O157:H7 and S. aureus during storage at abuse refrigeration temperature. Meat.Sci 2012;92(4):667-674.
  • Donelli D, Antonelli M, Bellinazzi C, Gensini GF, Firenzuoli F. Effects of lavender on anxiety: A systematic review and meta-analysis. Phytomedicine. 2019;65:153099.
  • Döner A, Tasci S. Effect of massage therapy with lavender oil on severity of restless legs syndrome and quality of life in hemodialysis patients. J Nurs Scholarsh 2022;54(3):304-314.
  • Doroshyenko O, Rokitta D, Zadoyan G, et al. Drug cocktail interaction study on the effect of the orally administered lavender oil preparation silexan on cytochrome P450 enzymes in healthy volunteers. Drug Metab Dispos. 2013 May;41(5):987-93.
  • Dos Reis Lucena L, Dos Santos-Junior JG, Tufik S, Hachul H. Lavender essential oil on postmenopausal women with insomnia: Double-blind randomized trial. Complement Ther Med 2021;59:102726.
  • Duan, X., Tashiro, M., Wu, D., Yambe, T., Wang, Q., Sasaki, T., Kumagai, K., Luo, Y., Nitta, S., and Itoh, M. Autonomic nervous function and localization of cerebral activity during lavender aromatic immersion. Technol Health Care 2007;15(2):69-78.
  • Dunn C, Sleep J, and Collett D. Sensing an improvement: an experimental study to evaluate the use of aromatherapy, massage and periods of rest in an intensive care unit. J Adv Nurs 1995;21(1):34-40.
  • Dwyer, A. V., Whitten, D. L., and Hawrelak, J. A. Herbal medicines, other than St. John’s Wort, in the treatment of depression: a systematic review. Altern Med Rev. 2011;16(1):40-49.
  • Ebrahimi S, Paryad E, Ghanbari Khanghah A, Pasdaran A, Kazemnezhad Leili E, Sadeghi Meibodi AM. The effects of lavandula aromatherapy on pain relief after coronary artery bypass graft surgery: A randomized clinical trial. Appl Nurs Res 2022;68:151638.
  • El-Alfy, A. T., Abourashed, E. A., and Matsumoto, R. R. Nature against depression. Curr Med Chem 2012;19(14):2229-2241.
  • Electronic Code of Federal Regulations. Title 21. Part 182 — Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  • Elegbede, J. A., Elson, C. E., Qureshi, A., Tanner, M. A., and Gould, M. N. Inhibition of DMBA-induced mammary cancer by the monoterpene d-limonene. Carcinogenesis 1984;5(5):661-664.
  • Elisabetsky, E., Marschner, J., and Souza, D. O. Effects of Linalool on glutamatergic system in the rat cerebral cortex. Neurochem.Res 1995;20(4):461-465.
  • Emami-Sigaroudi A, Salari A, Nourisaeed A, et al. Comparison between the effect of aromatherapy with lavender and damask rose on sleep quality in patients undergoing coronary artery bypass graft surgery: A randomized clinical trial. ARYA Atheroscler 2021;17(1):1-9.
  • Farshbaf-Khalili A, Kamalifard M, Namadian M. Comparison of the effect of lavender and bitter orange on anxiety in postmenopausal women: A triple-blind, randomized, controlled clinical trial. Complement Ther Clin Pract 2018;31:132-8.
  • Fetrow CW, Avila JR. Professional’s Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.
  • Firoozeei TS, Barekatain M, Karimi M, Zargaran A, Akhondzadeh S, Rezaeizadeh H. Lavender and dodder combined herbal syrup versus citalopram in major depressive disorder with anxious distress: A double-blind randomized trial. J Integr Med. 2020;18(5):409-415.
  • Firoozeei TS, Feizi A, Rezaeizadeh H, Zargaran A, Roohafza HR, Karimi M. The antidepressant effects of lavender (Lavandula angustifolia Mill.): A systematic review and meta-analysis of randomized controlled clinical trials. Complement Ther Med 2021;59:102679.
  • Franco L, Blanck TJ, Dugan K, Kline R, et al. Both lavender fleur oil and unscented oil aromatherapy reduce preoperative anxiety in breast surgery patients: a randomized trial. J Clin Anesth. 2016 Sep;33:243-89.
  • Fujii, M., Hatakeyama, R., Fukuoka, Y., Yamamoto, T., Sasaki, R., Moriya, M., Kanno, M., and Sasaki, H. Lavender aroma therapy for behavioral and psychological symptoms in dementia patients. Geriatr.Gerontol.Int 2008;8(2):136-138.
  • Gabbrielli G, Loggini F, Cioni PL, and et al. Activity of lavandino essential oil against non-tubercular opportunistic rapid grown mycobacteria. Pharmacol Res Commun 1988;20 Suppl 5:37-40.
  • Gamez MJ, Jimenez J, Navarro C, and et al. Study of the essential oil of Lavandula dentata L. Pharmazie 1990;45(1):69-70.
  • Gedney, J. J., Glover, T. L., and Fillingim, R. B. Sensory and affective pain discrimination after inhalation of essential oils. Psychosom.Med. 2004;66(4):599-606.
  • Genç F, Karadağ S, Kiliç Akça N, Tan M, Cerit D. The Effect of Aromatherapy on Sleep Quality and Fatigue Level of the Elderly: A Randomized Controlled Study. Holist Nurs Pract. 2020;34(3):155-162.
  • Generoso MB, Soares A, Taiar IT, Cordeiro Q, Shiozawa P. Lavender oil preparation (silexan) for treating anxiety: an updated meta-analysis. J Clin Psychopharmacol. 2017 Feb;37(1):115-17.
  • Ghaderi F, Solhjou N. The effects of lavender aromatherapy on stress and pain perception in children during dental treatment: A randomized clinical trial. Complement Ther Clin Pract. 2020;40:101182.
  • Ghavami T, Kazeminia M, Rajati F. The effect of lavender on stress in individuals: A systematic review and meta-analysis. Complement Ther Med 2022;68:102832.
  • Ghelardini C, Galeotti N, Salvatore G, and et al. Local anaesthetic activity of the essential oil of Lavandula angustifolia. Planta Med 1999;65(8):700-703.
  • Ghods AA, Abforosh NH, Ghorbani R, Asgari MR. The effect of topical application of lavender essential oil on the intensity of pain caused by the insertion of dialysis needles in hemodialysis patients: A randomized clinical trial. Complement Ther Med. 2015;23(3):325-30.
  • Goel N, Kim H, Lao RP. An olfactory stimulus modifies nighttime sleep in young men and women. Chronobiol Int 2005;22(5):889-904.
  • Graham PH, Browne L, Cox H, Graham J. Inhalation aromatherapy during radiotherapy: results of a placebo-controlled double-blind randomized trial. J Clin Oncol 2003;21:2372-6.
  • Gray SG, Clair AA. Influence of aromatherapy on medication administration to residential-care residents with dementia and behavioral challenges. Am J Alzheimers Dis Other Demen 2002;17(3):169-74.
  • Gross JJ, Levenson RW. Emotion elicitation using films. Int J Neurosci 1995;9:87-108.
  • Grunebaum, L. D., Murdock, J., Castanedo-Tardan, M. P., and Baumann, L. S. Effects of lavender olfactory input on cosmetic procedures. J Cosmet.Dermatol 2011;10(2):89-93.
  • Gürler M, Kizilirmak A, Baser M. The Effect of Aromatherapy on Sleep and Quality of Life in Menopausal Women with Sleeping Problems: A Non-Randomized, Placebo-Controlled Trial. Complement Med Res. 2020;27(6):421-430.
  • Haag, J. D. and Gould, M. N. Mammary carcinoma regression induced by perillyl alcohol, a hydroxylated analog of limonene. Cancer Chemother.Pharmacol 1994;34(6):477-483.
  • Hadi, N. and Hanid, A. A. Lavender essence for post-cesarean pain. Pak.J Biol.Sci 6-1-2011;14(11):664-667.
  • Hajhashemi V, Ghannadi A, Sharif B. Anti-inflammatory and analgesic properties of the leaf extracts and essential oil of Lavandula angustifolia Mill. J Ethnopharmacol 2003;89:67-71.
  • Hamzeh S, Safari-Faramani R, Khatony A. Effects of Aromatherapy with Lavender and Peppermint Essential Oils on the Sleep Quality of Cancer Patients: A Randomized Controlled Trial. Evid Based Complement Alternat Med. 2020;2020:7480204.
  • Hardy M, Kirk-Smith MD, and Stretch DD. Replacement of drug treatment for insomnia by ambient odour. Lancet 9-9-1995;346(8976):701.
  • Hashem-Dabaghian F, Ali Azimi S, Bahrami M, Latifi SA, Enayati A, Qaraaty M. Effect of lavender (Lavandula angustifolia L.) syrup on olfactory dysfunction in COVID-19 infection: A pilot controlled clinical trial. Avicenna J Phytomed 2022;12(1):1-7.
  • Hashemi SH, Hajbagheri A, Aghajani M. The effect of massage with lavender oil on restless leg syndrome in hemodialysis patients: a randomized controlled trial. Nurs Midwifery Stud. 2015 Dec;4(4):e29617.
  • Hassanzadeh M, Kiani F, Bouya S, Zarei M. Comparing the effects of relaxation technique and inhalation aromatherapy on fatigue in patients undergoing hemodialysis. Complement Ther Clin Pract. 2018;31:210-214.
  • Hay IC, Jamieson M, Ormerod AD. Randomized trial of aromatherapy. Successful treatment for alopecia areata. Arch Dermatol 1998;134:1349-52.
  • Henley DV, Lipson N, Korach KS, Bloch CA. Prepubertal gynecomastia linked to lavender and tea tree oils. N Eng J Med 2007;356:479-85.
  • Heuberger, E., Redhammer, S., and Buchbauer, G. Transdermal absorption of (-)-linalool induces autonomic deactivation but has no impact on ratings of well-being in humans. Neuropsychopharmacology 2004;29(10):1925-1932.
  • Hirokawa K, Nishimoto T, Taniguchi T. Effects of lavender aroma on sleep quality in healthy Japanese students. Perceptual and Motor Skills 2012;114(1):111-22.
  • Holmes C, Hopkins V, Hensford C, et al. Lavender oil as a treatment for agitated behaviour in severe dementia: a placebo controlled study. Int J Geriatr Psychiatry 2002;17(4):305-8.
  • Hongratanaworakit, T. Aroma-therapeutic effects of massage blended essential oils on humans. Nat.Prod.Commun. 2011;6(8):1199-1204.
  • Howard, S. and Hughes, B. M. Expectancies, not aroma, explain impact of lavender aromatherapy on psychophysiological indices of relaxation in young healthy women. Br J Health Psychol. 2008;13(Pt 4):603-617.
  • Hoya, Y., Matsumura, I., Fujita, T., and Yanaga, K. The use of nonpharmacological interventions to reduce anxiety in patients undergoing gastroscopy in a setting with an optimal soothing environment. Gastroenterol.Nurs. 2008;31(6):395-399.
  • Imura M, Misao H, Ushijima H. The psychological effects of aromatherapy-massage in healthy postpartum mothers. J Midwifery Womens Health 2006;51(2):e21-e27.
  • Itai T, Amayasu H, Kuribayashi M, and et al. Psychological effects of aromatherapy on chronic hemodialysis patients. Psychiatry Clin Neurosci 2000;54(4):393-397.
  • Jager W, Buchbauer G, Jirovetz L, and et al. Percutaneous absorption of lavender oil from massage oil. J Soc Cosmet Chem 1992;43:49-54.
  • Jimbo, D., Kimura, Y., Taniguchi, M., Inoue, M., and Urakami, K. Effect of aromatherapy on patients with Alzheimer’s disease. Psychogeriatrics. 2009;9(4):173-179.
  • Jones T, Purdy M, Stewart EA, et al. Lavender aromatherapy to reduce anxiety during intrauterine insemination: A randomized controlled trial. Glob Adv Health Med 2021;10:21649561211059074.
  • Jones, C. The efficacy of lavender oil on perineal trauma: a review of the evidence. Complement Ther Clin Pract. 2011;17(4):215-220.
  • Kane FM, Brodie EE, Coull A, et al. The analgesic effect of odour and music upon dressing change. Br J Nurs 2004;13(19):S4-12.
  • Kang HJ, Nam ES, Lee Y, Kim M. How strong is the evidence for the anxiolytic efficacy of lavender?: Systematic review and meta-analysis of randomized controlled trials. Asian Nurs Res (Korean Soc Nurs Sci). 2019;13(5):295-305.
  • Kang HY, Na SS and Kim YK. [Effects of oral care with essential oil on improvement in oral health status of hospice patients]. J Korean Acad Nurs 2010;40(4):473-481.
  • Karaman S, Karaman T, Tapar H, Dogru S, Suren M. A randomized placebo-controlled study of aromatherapy for the treatment of postoperative nausea and vomiting. Complement Ther Med 2019;42:417-21. doi: 10.1016/j.ctim.2018.12.019.
  • Karaman T, Karaman S, Dogru S, Tapar H, et al. Evaluating the efficacy of lavender aromatherapy on peripheral venous cannulation pain and anxiety: a prospective, randomized study. Complement Ther Clin Pract. 2016 May;23:64-8.
  • Karan NB. Influence of lavender oil inhalation on vital signs and anxiety: A randomized clinical trial. Physiol Behav. 2019;211:112676.
  • Karimzadeh Z, Azizzadeh Forouzi M, Rahiminezhad E, Ahmadinejad M, Dehghan M. The Effects of Lavender and Citrus aurantium on Anxiety and Agitation of the Conscious Patients in Intensive Care Units: A Parallel Randomized Placebo-Controlled Trial. Biomed Res Int 2021;2021:5565956.
  • Kasper S, Gastpar M, Müller WE, et al. Lavender oil preparation Silexan is effective in generalized anxiety disorder–a randomized, double-blind comparison to placebo and paroxetine. Int J Neuropsychopharmacol. 2014 Jun;17(6):859-69.
  • Kasper, S., Gastpar, M., Muller, W. E., Volz, H. P., Moller, H. J., Dienel, A., and Schlafke, S. Efficacy and safety of silexan, a new, orally administered lavender oil preparation, in subthreshold anxiety disorder – evidence from clinical trials. Wien Med Wochenschr. 2010;160(21-22):547-556.
  • Kasper, S., Gastpar, M., Muller, W. E., Volz, H. P., Moller, H. J., Dienel, A., and Schlafke, S. Silexan, an orally administered Lavandula oil preparation, is effective in the treatment of ‘subsyndromal’ anxiety disorder: a randomized, double-blind, placebo controlled trial. Int Clin Psychopharmacol. 2010;25(5):277-287.
  • Kazeminia M, Abdi A, Vaisi-Raygani A, et al. The Effect of Lavender (Lavandula stoechas L.) on Reducing Labor Pain: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2020;2020:4384350.
  • Kazemzadeh R, Nikjoue R, Rostamnegad M, Norouzi H. Effect of lavender aromatherapy on menopause hot flushing: a crossover randomized clinical trial. J Chin Med Assoc. 2016 Sep;79(9):489-92.
  • Kianpour M, Mansouri A, Mehrabi T, Asghari G. Effect of lavender scent inhalation on prevention of stress, anxiety, and depression in the postpartum period. Iran J Nurs Midwifery Res. 2016 Mar-Apr;21(2):197-201.
  • Kim, M. J., Nam, E. S., and Paik, S. I. [The effects of aromatherapy on pain, depression, and life satisfaction of arthritis patients]. Taehan Kanho.Hakhoe.Chi 2005;35(1):186-194.
  • Kim, S., Kim, H. J., Yeo, J. S., Hong, S. J., Lee, J. M., and Jeon, Y. The effect of lavender oil on stress, bispectral index values, and needle insertion pain in volunteers. J Altern Complement Med 2011;17(9):823-826.
  • Kodama T, Watanabe T, Mataki N, Kanoh S, Kichikawa Y. Acute eosinophilic pneumonia following aromatherapy with essential oil. Respir Med Case Rep 2022;37:101657.
  • Kritsidima, M., Newton, T., and Asimakopoulou, K. The effects of lavender scent on dental patient anxiety levels: a cluster randomised-controlled trial. Community Dent Oral Epidemiol 2010;38(1):83-87.
  • Kutlu, A. K. Yilmaz E. et al. Effects of aroma inhalation on examination anxiety. Teaching & Learning in Nursing 2008;3(4):125-130.
  • Lantry LE, Zhang Z, Gao F, and et al. Chemopreventive effect of perillyl alcohol on 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanone induced tumorigenesis in (C3H/HeJ X A/J)F1 mouse lung. J Cell Biochem Suppl 1997;27:20-25.
  • Lee, S. Y. [The effect of lavender aromatherapy on cognitive function, emotion, and aggressive behavior of elderly with dementia]. Taehan Kanho Hakhoe Chi 2005;35(2):303-312.
  • Lehrner J, Marwinski G, Lehr S, et al. Ambient odors of orange and lavender reduce anxiety and improve mood in a dental office. Physiol Behav 2005;86(1-2):92-5.
  • Lewith GT, Godfrey AD, Prescott P. A single-blinded, randomized pilot study evaluating the aroma of Lavandula augustifolia as a treatment for mild insomnia. J Altern Complement Med 2005;11:631-7.
  • Li D, Li Y, Bai X, Wang M, Yan J, Cao Y. The effects of aromatherapy on anxiety and depression in people with cancer: a systematic review and meta-analysis. Front Public Health 2022;10:853056.
  • Lillehei AS, Halcón LL, Savik K, Reis R. Effect of Inhaled Lavender and Sleep Hygiene on Self-Reported Sleep Issues: A Randomized Controlled Trial. J Altern Complement Med. 2015;21(7):430-8.
  • Lin PW, Chan W, Ng BF, Lam LC. Efficacy of aromatherapy (Lavandula angustifolia) as an intervention for agitated behaviours in Chinese older persons with dementia: a cross-over randomized trial. Int J Geriatr Psychiatry 2007;22:405-10.
  • Lis-Balchin, M. and Hart, S. A preliminary study of the effect of essential oils on skeletal and smooth muscle in vitro. J Ethnopharmacol 1997;58(3):183-187.
  • Lis-Balchin, M. and Hart, S. Studies on the mode of action of the essential oil of lavender (Lavandula angustifolia P. Miller). Phytother Res 1999;13(6):540-542.
  • Louis, M. and Kowalski, S. D. Use of aromatherapy with hospice patients to decrease pain, anxiety, and depression and to promote an increased sense of well-being. Am.J Hosp.Palliat.Care 2002;19(6):381-386.
  • Lytle J, Mwatha C, Davis KK. Effect of lavender aromatherapy on vital signs and perceived quality of sleep in the intermediate care unit: a pilot study. Am J Crit Care. 2014;23(1):24-9.
  • Mahdavikian S, Fallahi M, Khatony A. Comparing the Effect of Aromatherapy with Peppermint and Lavender Essential Oils on Fatigue of Cardiac Patients: A Randomized Controlled Trial. Evid Based Complement Alternat Med 2021;2021:9925945.
  • Maya-Enero S, Fàbregas-Mitjans M, Llufriu-Marquès RM, Candel-Pau J, Garcia-Garcia J, López-Vílchez MÁ. Analgesic effect of inhaled lavender essential oil for frenotomy in healthy neonates: a randomized clinical trial. World J Pediatr. 2022;18(6):398-403.
  • Maya-Enero S, Fàbregas-Mitjans M, Llufriu-Marquès RM, Candel-Pau J, Garcia-Garcia J, López-Vílchez MÁ. Comparison of the analgesic effect of inhaled lavender vs vanilla essential oil for neonatal frenotomy: a randomized clinical trial (NCT04867824). Eur J Pediatr 2022;181(11):3923-3929.
  • McCaffrey R, Thomas DJ, Kinzelman AO. The effects of lavender and rosemary essential oils on test-taking anxiety among graduate nursing students. Holist Nurs Pract 2009;23(2):88-93.
  • Mills, J. J., Chari, R. S., Boyer, I. J., Gould, M. N., and Jirtle, R. L. Induction of apoptosis in liver tumors by the monoterpene perillyl alcohol. Cancer Res 3-1-1995;55(5):979-983.
  • Mirbagher Ajorpaz N, Rahemi Z, Aghajani M, Hashemi SH. Effects of glycerin oil and lavender oil massages on hemodialysis patients’ restless legs syndrome. J Bodyw Mov Ther. 2020;24(1):88-92.
  • Mohammad Rezaie S, Shahabinejad M, Loripoor M, Sayadi AR. The effect of aromatherapy with lavender essential oil on the working memory of women with multiple sclerosis. J Med Life 2021;14(6):776-781.
  • Mojtehedi M, Salehi-Pourmehr H, Ostadrahimi A, Asnaashari S, Esmaeilpour K, Farshbaf-Khalili A. Effect of aromatherapy with essential oil of Lavandula angustifolia Mill- Citrus bergamia and mindfulness-based intervention on sexual function, anxiety, and depression in postmenopausal women: A randomized controlled trial with factorial design. Iran J Nurs Midwifery Res. 2022:392-405.
  • Möller HJ, Volz HP, Dienel A, Schläfke S, Kasper S. Efficacy of Silexan in subthreshold anxiety: meta-analysis of randomised, placebo-controlled trials. Eur Arch Psychiatry Clin Neurosci 2017 Nov 17. doi: 10.1007/s00406-017-0852-4.
  • Moorman Li R, Gilbert B, Orman A,et al. Evaluating the effects of diffused lavender in an adult day care center for patients with dementia in an effort to decrease behavioral issues: a pilot study. J Drug Assess. 2017 Jan 23;6(1):1-5.
  • Morris N. The effects of lavender (Lavendula angustifolium) baths on psychological well-being: two exploratory randomised control trials. Complement Ther Med 2002;10:223-8.
  • Moss M, Cook J, Wesnes K, Duckett P. Aromas of rosemary and lavender essential oils differentially affect cognition and mood in healthy adults. Int J Neurosci 2003;113(1):15-38.
  • Motaghi N, Tajadini H, Shafiei K, et al. Lavender improves fatigue symptoms in multiple sclerosis patients: A double-blind, randomized controlled trial. Mult Scler Relat Disord 2022;65:104000.
  • Motomura N, Sakurai A, and Yotsuya Y. A psychophysiological study of lavender odorant. Memoirs of Osaka Kyoiku University, Series III 1999;47(2):281-287.
  • Motomura, N., Sakurai, A., and Yotsuya, Y. Reduction of mental stress with lavender odorant. Percept.Mot.Skills 2001;93(3):713-718.
  • Muzzarelli L, Force M, Sebold M. Aromatherapy and reducing preprocedural anxiety: A controlled prospective study. Gastroenterol Nurs 2006;29(6):466-71.
  • Nasiri A, Hahmodi MA, Nobakht Z. Effect of aromatherapy massage with lavender essential oil on pain in patients with osteoarthritis of the knee: a randomized controlled clinical trial. Complement Ther Clin Pract. 2016 Nov;25:75-80.
  • Nasiri Lari Z, Hajimonfarednejad M, Riasatian M, et al. Efficacy of inhaled Lavandula angustifolia Mill. Essential oil on sleep quality, quality of life and metabolic control in patients with diabetes mellitus type II and insomnia. J Ethnopharmacol. 2020;251:112560.
  • Nasiri M, Asayesh H, Yousefi Khosroabadi Z, Hosseini Amiri M, Bahadori H, Rajaee M. Effects of Aromatherapy with Lavender (Lavandula angustifolia MILL) on Post-Dural Puncture Headache: A Randomized Placebo-Controlled Trial. Altern Ther Health Med. 2020:AT6279.
  • Nelson RR. In-vitro activities of five plant essential oils against methicillin- resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium. J Antimicrob Chemother 1997;40(2):305-307.
  • Nikjou R, Kazemzadeh R, Rostamnegad M, Moshfegi S, Karimollahi M, Salehi H. The effect of lavender aromatherapy on the pain severity of primary dysmenorrhea: a triple-blind randomized clinical trial. Ann Med Health Sci Res. 2016 Jul-Aug;6(4):211-15.
  • Nord D, Belew J. Effectiveness of the essential oils lavender and ginger in promoting children’s comfort in a perianesthesia setting. J Perianesth Nurs. 2009;24:307-12.
  • O’Connor DW, Eppingstall B, Taffe J, van der Ploeg ES. A randomized, controlled cross-over trial of dermally-applied lavender (Lavandula angustifolia) oil as a treatment of agitated behaviour in dementia. BMC Complement Altern Med. 2013;13:315.
  • Oshvandi K, Mirzajani Letomi F, Soltanian AR, Shamsizadeh M. The effects of foot massage on hemodialysis patients’ sleep quality and restless leg syndrome: a comparison of lavender and sweet orange essential oil topical application. J Complement Integr Med 2021;18(4):843-850.
  • Ostermann, T., Blaser, G., Bertram, M., Michalsen, A., Matthiessen, P. F., and Kraft, K. Effects of rhythmic embrocation therapy with solum oil in chronic pain patients: a prospective observational study. Clin J Pain 2008;24(3):237-243.
  • Ou, M. C., Hsu, T. F., Lai, A. C., Lin, Y. T., and Lin, C. C. Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial. J Obstet.Gynaecol.Res 2012;38(5):817-822.
  • Ozkaraman A, Dügüm Ö, Özen Yilmaz H, Usta Yesilbalkan Ö. Aromatherapy: The Effect of Lavender on Anxiety and Sleep Quality in Patients Treated With Chemotherapy. Clin J Oncol Nurs 2018;22(2):203-10.
  • Perry, R., Terry, R., Watson, L. K., and Ernst, E. Is lavender an anxiolytic drug? A systematic review of randomised clinical trials. Phytomedicine. 6-15-2012;19(8-9):825-835.
  • Politano VT, McGinty D, Lewis EM, et al. Uterotrophic assay of percutaneous lavender oil in immature female rats. Int J Toxicol. 2013 Mar-Aor;32(2):123-9.
  • Prusinowska R, Smigielski KB. Composition, biological properties and therapeutic effects of lavender (Lavandula angustifolia L.). A review. Herba Polonica. 2014;60(2):56-66.
  • Rademaker M. Allergic contact dermatitis from lavender fragrance in Difflam gel. Contact Dermatitis 1994;31(1):58-59.
  • Rahimi E, Sedighi Chafjiri A, Hasavari F, Kazem Nezhad Leyli E, Naseri M, Khosravi M. Evaluation of the effect of lavender aroma on fatigue among hemodialysis patients. Holist Nurs Pract 2022;36(2):76-84.
  • Raisi Dehkordi Z, Hosseini Baharanchi FS, Bekhradi R. Effect of lavender inhalation on the symptoms of primary dysmenorrhea and the amount of menstrual bleeding: A randomized clinical trial. Complement Ther Med. 2014 Apr;22(2):212-9. doi: 10.1016/j.ctim.2013.12.011. Epub 2014 Jan 6.
  • Razaghi N, Aemmi SZ, Sadat Hoseini ASS, Boskabadi H, Mohebbi T, Ramezani M. The effectiveness of familiar olfactory stimulation with lavender scent and glucose on the pain of blood sampling in term neonates: A randomized controlled clinical trial. Complement Ther Med. 2020;49:102289.
  • Reddy, B. S., Wang, C. X., Samaha, H., Lubet, R., Steele, V. E., Kelloff, G. J., and Rao, C. V. Chemoprevention of colon carcinogenesis by dietary perillyl alcohol. Cancer Res 2-1-1997;57(3):420-425.
  • Reddy, K. K., Grossman, L., and Rogers, G. S. Common complementary and alternative therapies with potential use in dermatologic surgery: risks and benefits. J Am Acad Dermatol 2013;68(4):e127-e135.
  • Ren, Z. and Gould, M. N. Inhibition of ubiquinone and cholesterol synthesis by the monoterpene perillyl alcohol. Cancer Lett 1-30-1994;76(2-3):185-190.
  • Rho KH, Han SH, Kim KS, Lee MS. Effects of aromatherapy massage on anxiety and self-esteem in korean elderly women: a pilot study. Int J Neurosci 2006;116(12):1447-55.
  • Ripple GH, Gould MN, Stewart JA, and et al. Phase I clinical trial of perillyl alcohol administered daily. Clin Cancer Res 1998;4(5):1159-1164.
  • Ripple, G. H., Gould, M. N., Arzoomanian, R. Z., Alberti, D., Feierabend, C., Simon, K., Binger, K., Tutsch, K. D., Pomplun, M., Wahamaki, A., Marnocha, R., Wilding, G., and Bailey, H. H. Phase I clinical and pharmacokinetic study of perillyl alcohol administered four times a day. Clin Cancer Res 2000;6(2):390-396.
  • Rivaz M, Rahpeima M, Khademian Z, Dabbaghmanesh MH. The effects of aromatherapy massage with lavender essential oil on neuropathic pain and quality of life in diabetic patients: A randomized clinical trial. Complement Ther Clin Pract 2021;44:101430.
  • S PK, Aafaque S, S S, N N. Effect of aromatherapy on dental anxiety among orthodontic patients: A randomized controlled trial. Cureus. 2019;11(8):e5306.
  • Saeki Y. The effect of foot-bath with or without the essential oil of lavender on the autonomic nervous system: a randomized trial. Complement Ther Med 2000;8(1):2-7.
  • Sakamoto, R., Minoura, K., Usui, A., Ishizuka, Y., and Kanba, S. Effectiveness of aroma on work efficiency: lavender aroma during recesses prevents deterioration of work performance. Chem Senses 2005;30(8):683-691.
  • Sakamoto, Y., Ebihara, S., Ebihara, T., Tomita, N., Toba, K., Freeman, S., Arai, H., and Kohzuki, M. Fall prevention using olfactory stimulation with lavender odor in elderly nursing home residents: a randomized controlled trial. J Am Geriatr.Soc 2012;60(6):1005-1011.
  • Salehi-Pourmehr H, Ostadrahimi A, Ebrahimpour-Mirzarezaei M, Farshbaf-Khalili A. Does aromatherapy with lavender affect physical and psychological symptoms of menopausal women? A systematic review and meta-analysis. Complement Ther Clin Pract. 2020;39:101150.
  • Sarrell, E. M., Cohen, H. A., and Kahan, E. Naturopathic treatment for ear pain in children. Pediatrics 2003;111(5 Pt 1):e574-e579.
  • Sasannejad P, Saeedi M, Shoeibi A, et al. Lavender essential oil in the treatment of migraine headache: a placebo-controlled clinical trial. Eur Neurol 2012;67(5):288-91.
  • Sayorwan, W., Siripornpanich, V., Piriyapunyaporn, T., Hongratanaworakit, T., Kotchabhakdi, N., and Ruangrungsi, N. The effects of lavender oil inhalation on emotional states, autonomic nervous system, and brain electrical activity. J Med Assoc Thai. 2012;95(4):598-606.
  • Seiiedi-Biarag L, Mirghafourvand M. The effect of lavender on mothers sleep quality in the postpartum period: a systematic review and meta-analysis. J Complement Integr Med 2022.
  • Sentürk A, Tekinsoy Kartin P. The effect of lavender oil application via inhalation pathway on hemodialysis patients’ anxiety level and sleep quality. Holist Nurs Pract 2018;32(6):324-35. doi: 10.1097/HNP.0000000000000292.
  • Sgoutas-Emch, S. Fox T. Preston M. Brooks C. Serber E. Stress management: aromatherapy as an alternative. Scientific Review of Alternative Medicine 2001;5(2):90-95.
  • Shammas RL, Marks CE, Broadwater G, et al. The effect of lavender oil on perioperative pain, anxiety, depression, and sleep after microvascular breast reconstruction: A prospective, single-blinded, randomized, controlled trial. J Reconstr Microsurg 2021;37(6):530-540.
  • Sheikhan, F., Jahdi, F., Khoei, E. M., Shamsalizadeh, N., Sheikhan, M., and Haghani, H. Episiotomy pain relief: Use of Lavender oil essence in primiparous Iranian women. Complement Ther Clin Pract. 2012;18(1):66-70.
  • Shimada, K., Fukuda, S., Maeda, K., Kawasaki, T., Kono, Y., Jissho, S., Taguchi, H., Yoshiyama, M., and Yoshikawa, J. Aromatherapy alleviates endothelial dysfunction of medical staff after night-shift work: preliminary observations. Hypertens.Res 2011;34(2):264-267.
  • Smith DS, Helzner EC, Nuttall CE Jr, et al. Failure of zinc gluconate in treatment of acute upper respiratory tract infections. Antimicrob Agents Chemother 1989;33:646-8.
  • Snow LA, Hovanec L, Brandt J. A controlled trial of aromatherapy for agitation in nursing home patients with dementia. J Altern Complement Med 2004;10(3):431-7.
  • Soden K, Vincent K, Craske S, et al. A randomized controlled trial of aromatherapy massage in a hospice setting. Palliat Med 2004;18(2):87-92.
  • Soltani R, Soheilipour S, Hajhashemi V, Asghari G, Bagheri M, Molavi M. Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial. Int J Pediatr Otorhinolaryngol. 2013 Sep;77(9):1579-81. doi: 10.1016/j.ijporl.2013.07.014.
  • Toda, M. and Morimoto, K. Effect of lavender aroma on salivary endocrinological stress markers. Arch.Oral Biol. 2008;53(10):964-968.
  • Tugut N, Demirel G, Baser M, Ata EE, Karakus S. Effects of lavender scent on patients’ anxiety and pain levels during gynecological examination. Complement Ther Clin Pract 2017 Aug;28:65-9.
  • Uehleke, B., Schaper, S., Dienel, A., Schlaefke, S., and Stange, R. Phase II trial on the effects of Silexan in patients with neurasthenia, post-traumatic stress disorder or somatization disorder. Phytomedicine. 6-15-2012;19(8-9):665-671.
  • Usta C, Tanyeri-Bayraktar B, Bayraktar S. Pain control with lavender oil in premature infants: a double-blind randomized controlled study. J Altern Complement Med. 2020.
  • Vakilian, K., Atarha, M., Bekhradi, R., and Chaman, R. Healing advantages of lavender essential oil during episiotomy recovery: a clinical trial. Complement Ther Clin Pract. 2011;17(1):50-53.
  • Varaei S, Jalalian Z, Yekani Nejad MS, Shamsizadeh M. Comparison the effects of inhalation and massage aromatherapy with lavender and sweet orange on fatigue in hemodialysis patients: a randomized clinical trial. J Complement Integr Med. 2020.
  • Varma S, Blackford S, Statham BN, Blackwell A. Combined contact allergy to tea tree oil and lavender oil complicating chronic vulvovaginitis. Contact Dermatitis 2000;42:309-10.
  • Vaziri F, Khosropoor M, Hidari M, Pourahmad S, Morshed Behbahani B, Saki F. The effect of aromatherapy by lavender oil on infant vaccination pain: a double blind randomized controlled trial. J Caring Sci. 2019;8(1):17-21.
  • Vaziri F, Shiravani M, Najib FS, Pourahmad S, Salehi A, Yazdanpanahi Z. Effect of lavender oil aroma in the early hours of postpartum period on maternal pains, fatigue, and mood: a randomized clinical trial. Int J Prev Med. 2017 May 4;8:29.
  • Velasco-Rodríguez R, Pérez-Hernández MG, Maturano-Melgoza JA, et al. The effect of aromatherapy with lavender (Lavandula angustifolia) on serum melatonin levels. Complement Ther Med. 2019;47:102208.
  • Watson K, Hatcher D, Good A. A randomised controlled trial of Lavender (Lavandula Angustifolia) and Lemon Balm (Melissa Officinalis) essential oils for the treatment of agitated behaviour in older people with and without dementia. Complement Ther Med 2019;42:366-73. doi: 10.1016/j.ctim.2018.12.016.
  • Woelk, H. and Schlafke, S. A multi-center, double-blind, randomised study of the Lavender oil preparation Silexan in comparison to Lorazepam for generalized anxiety disorder. Phytomedicine. 2010;17(2):94-99.
  • Woronuk, G., Demissie, Z., Rheault, M., and Mahmoud, S. Biosynthesis and therapeutic properties of Lavandula essential oil constituents. Planta Med 2011;77(1):7-15.
  • Xiong M, Li Y, Tang P, Zhang Y, Cao M, Ni J, Xing M. Effectiveness of aromatherapy massage and inhalation on symptoms of depression in Chinese community-dwelling older adults. J Altern Complement Med. 2018;24(7):717-724.
  • Xu, F., Uebaba, K., Ogawa, H., Tatsuse, T., Wang, B. H., Hisajima, T., and Venkatraman, S. Pharmaco-physio-psychologic effect of Ayurvedic oil-dripping treatment using an essential oil from Lavendula angustifolia. J Altern.Complement Med. 2008;14(8):947-956.
  • Yamada K, Kimaki Y, and Ashida Y. Anticonvulsive effects of inhaling lavender oil vapour. Biol Pharm Bull 1994;17(2):359-360.
  • Yap WS, Dolzhenko AV, Jalal Z, Hadi MA, Khan TM. Efficacy and safety of lavender essential oil (Silexan) capsules among patients suffering from anxiety disorders: A network meta-analysis. Sci Rep. 2019;9(1):18042.
  • Yazdkhasti M, Pirak A. The effect of aromatherapy with lavender essence on severity of labor pain and duration of labor in primiparous women. Complement Ther Clin Pract. 2016 Nov;25:81-86.
  • Yip, Y. B. and Tse, S. H. An experimental study on the effectiveness of acupressure with aromatic lavender essential oil for sub-acute, non-specific neck pain in Hong Kong. Complement Ther Clin Pract 2006;12(1):18-26.
  • Yip, Y. B. and Tse, S. H. The effectiveness of relaxation acupoint stimulation and acupressure with aromatic lavender essential oil for non-specific low back pain in Hong Kong: a randomised controlled trial. Complement Ther.Med. 2004;12(1):28-37.

Nettle

  • Anon. Quercetin. Alt Med Rev 1998;3:140-3.
  • Bakhshaee M, Mohammadpour AH, Esmaeili M, et al. Efficacy of a supportive therapy of allergic rhinitis by stinging nettle (Urtica dioica) root extract: a randomized, double-blind, placebo-controlled clinical trial. IJPR 2017;16(Special Issue):112-118.
  • Balzarini, J., Neyts, J., Schols, D., Hosoya, M., Van Damme, E., Peumans, W., and De Clercq, E. The mannose-specific plant lectins from Cymbidium hybrid and Epipactis helleborine and the (N-acetylglucosamine)n-specific plant lectin from Urtica dioica are potent and selective inhibitors of human immunodeficiency virus and cytomegalovirus replication in vitro. Antiviral Res 1992;18(2):191-207.
  • Baykul, T., Alanoglu, E. G., and Kocer, G. Use of Ankaferd Blood Stopper as a hemostatic agent: a clinical experience. J Contemp Dent Pract 2010;11(1):E088-E094.
  • Bercovich, E. and Saccomanni, M. Analysis of the results obtained with a new phytotherapeutic association for LUTS versus control. [corrected]. Urologia. 2010;77(3):180-186.
  • Beyazit, Y., Kurt, M., Kekilli, M., Goker, H., and Haznedaroglu, I. C. Evaluation of hemostatic effects of Ankaferd as an alternative medicine. Altern.Med.Rev. 2010;15(4):329-336.
  • Bombardelli E and Morazzoni P. Urtica dioica L. Fitoterapia 1997;68(5):387-402.
  • Cabeza M, Bratoeff E, Heuze I, et al. Effect of beta-sitosterol as inhibitor of 5 alpha-reductase in hamster prostate. Proc West Pharmacol Soc 2003;46:153-5.
  • Cai, T., Mazzoli, S., Bechi, A., Addonisio, P., Mondaini, N., Pagliai, R. C., and Bartoletti, R. Serenoa repens associated with Urtica dioica (ProstaMEV) and curcumin and quercitin (FlogMEV) extracts are able to improve the efficacy of prulifloxacin in bacterial prostatitis patients: results from a prospective randomised study. Int.J Antimicrob.Agents 2009;33(6):549-553.
  • Caliskaner Z, Karaayvaz M, Ozturk S. Misuse of a herb: stinging nettle (Urtica urens) induced severe tongue oedema. Complement Ther Med 2004;12:57-8.
  • Christensen, R. and Bliddal, H. Is Phytalgic(R) a goldmine for osteoarthritis patients or is there something fishy about this nutraceutical? A summary of findings and risk-of-bias assessment. Arthritis Res.Ther. 2010;12(1):105.
  • Chrubasik S, Enderlein W, Bauer R, and Grabner W. Evidence for antirheumatic effectiveness of Herba Urticae dioicae in acute arthritis: A pilot study. Phytomedicine 1997;4(2):105-108.
  • Chrubasik, J. E., Roufogalis, B. D., Wagner, H., and Chrubasik, S. A comprehensive review on the stinging nettle effect and efficacy profiles. Part II: urticae radix. Phytomedicine. 2007;14(7-8):568-579.
  • Chrubasik, J. E., Roufogalis, B. D., Wagner, H., and Chrubasik, S. A. A comprehensive review on nettle effect and efficacy profiles, Part I: herba urticae. Phytomedicine. 2007;14(6):423-435.
  • Czarnetzki, B. M., Thiele, T., and Rosenbach, T. Immunoreactive leukotrienes in nettle plants (Urtica urens). Int Arch Allergy Appl.Immunol. 1990;91(1):43-46.
  • Dathe G and Schmid H. [Phytotherapy of the benign prostatic hyperplasia (BPH). Double-blind study with an extract of Radicus Urticae (ERU)]. Urologe B 1987;27:223-226.
  • Durak I, Biri H, Devrim E, et al. Aqueous extract of Urtica dioica makes significant inhibition on adenosine deaminase activity in prostate tissue from patients with prostate cancer. Cancer Biol Ther 2004;3:855-7.
  • Easton L, Vaid S, Nagel AK, Venci JV, Fortuna RJ. Stinging Nettle (Urtica dioica): An Unusual Case of Galactorrhea. Am J Case Rep 2021;22:e933999.
  • Engelmann U, Boos G, and Kres H. [Therapy of benign prostatic hyperplasia with Bazoton liquidum]. Urologe B 1996;36:287-291.
  • Eyi, E. G., Engin-Ustun, Y., Kaba, M., and Mollamahmutoglu, L. Ankaferd blood stopper in episiotomy repair. Clin Exp Obstet Gynecol 2013;40(1):141-143.
  • Farzami B, Ahmadvand D, Vardasbi S, Majin FJ, Khaghani Sh. Induction of insulin secretion by a component of Urtica dioica leave extract in perifused Islets of Langerhans and its in vivo effects in normal and streptozotocin diabetic rats. J Ethnopharmacol. 2003;89(1):47-53.
  • Fischer M and Wilbert D. [Efficacy testing of a phytopharmacon in the treatment of benign prostate hyperplasia (BPH)]. In: Rutishauser G. Benigne Prostatahyperplasie. Munchen: Zuckerscherdt;1992.
  • Francois, K. O., Auwerx, J., Schols, D., and Balzarini, J. Simian immunodeficiency virus is susceptible to inhibition by carbohydrate-binding agents in a manner similar to that of HIV: implications for further preclinical drug development. Mol.Pharmacol. 2008;74(2):330-337.
  • Gansser D and Spiteller G. Aromatase inhibitors from Urtica dioica roots. Planta Medica 1995;61:138-140.
  • Goetz P. [Treatment of benign prostate hyperplasia with nettle roots]. Zeitschrift für Phytotherapie 1989;10:175-178.
  • Hallwachs, O. [Urination disorders caused by prostatic hyperplasia. Effect of Bazoton, Harzol and Prosta-capsules]. MMW.Munch.Med Wochenschr. 10-30-1981;123(44):1675-1676.
  • Hartmann RW, Mark M, and Soldati F. Inhibition of a 5 a-reductase and aromatase by PHL-00801 (Prostatonin®), a combination of PY102 (Pygeum africanum) and UR 102 (Urtica dioica) extracts. Phytomedicine 1996;3(2):121-128.
  • Hill, N., Stam, C., and van Haselen, R. A. The efficacy of Prrrikweg gel in the treatment of insect bites: a double-blind, placebo-controlled clinical trial. Pharm World Sci 1996;18(1):35-41.
  • Hill, N., Stam, C., Tuinder, S., and van Haselen, R. A. A placebo controlled clinical trial investigating the efficacy of a homeopathic after-bite gel in reducing mosquito bite induced erythema. Eur J Clin Pharmacol 1995;49(1-2):103-108.
  • Hirano, T., Homma, M., and Oka, K. Effects of stinging nettle root extracts and their steroidal components on the Na+,K(+)-ATPase of the benign prostatic hyperplasia. Planta Med 1994;60(1):30-33.
  • Hryb, D. J., Khan, M. S., Romas, N. A., and Rosner, W. The effect of extracts of the roots of the stinging nettle (Urtica dioica) on the interaction of SHBG with its receptor on human prostatic membranes. Planta Med 1995;61(1):31-32.
  • Huber, R., Bross, F., Schempp, C., and Grundemann, C. Arnica and stinging nettle for treating burns – a self-experiment. Complement Ther.Med. 2011;19(5):276-280.
  • Jacquet, A., Girodet, P. O., Pariente, A., Forest, K., Mallet, L., and Moore, N. Phytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial. Arthritis Res.Ther. 2009;11(6):R192.
  • Kassen A, Berges R, Senge T, et al. Effect of beta-sitosterol on transforming growth factor-beta-1 expression and translocation protein kinase C alpha in human prostate stromal cells in vitro. Eur Urol 2000;37:735-41.
  • Khalili N, Fereydoonzadeh R, Mohtashami R, Mehrzadi S, Heydari M, Huseini F. Silymarin, Olibanum, and Nettle, a mixed herbal formulation in the treatment of Type II Diabetes: a randomized, double-blind, placebo-controlled, clinical trial. J Evid Based Complementary Altern Med. 2017 Oct;22(4):603-608.
  • Khosravi MH, Atefi A, Mehri A, et al. Therapeutic effects of Rosa canina, Urtica dioica and Tanacetum vulgare herbal combination in treatment of tinnitus symptoms: A double-blind randomised clinical trial. Clin Otolaryngol 2022.
  • Kianbakht S, Khalighi-Sigaroodi F, Dabaghian FH. Improved glycemic control in patients with advanced type 2 diabetes mellitus taking Urtica dioica leaf extract: a randomized double-blind placebo-controlled clinical trial. Clin. Lab. 2013;59:1071-1076.
  • Klingelhoefer, S., Obertreis, B., Quast, S., and Behnke, B. Antirheumatic effect of IDS 23, a stinging nettle leaf extract, on in vitro expression of T helper cytokines. J Rheumatol. 1999;26(12):2517-2522.
  • Koch, E. Extracts from Fruits of Saw Palmetto (Sabal serrulata) and Roots of Stinging Nettle (Urtica dioica): Viable Alternatives in the Medical Treatment of Benign Prostatic Hyperplasia and Associated Lower Urinary Tracts Symptoms. Planta Med 2001;67(6):489-500.
  • Konieczynski, P. and Wesolowski, M. Water-extractable magnesium, manganese and copper in leaves and herbs of medicinal plants. Acta Pol.Pharm. 2012;69(1):33-39.
  • Konrad L, Muller HH, Lenz C, et al. Antiproliferative effect on human prostate cancer cells by a stinging nettle root (Urtica dioica) extract. Planta Med 2000;66:44-7.
  • Kraus R, Spiteller G, and Bartsch W. [(10E,12Z)-9-Hydroxy-10,12-octadecadienoic acid, an aromatase inhibitor from roots of Urtica dioica]. Liebigs Ann Chem 1991;335-339.
  • Krystofova O, Adam V, Babula P, et al. Effects of Various Doses of Selenite on Stinging Nettle (Urtica dioica L.). Int J Environ Res Public Health. 2010 Oct;7(10):3804-15.
  • Krzeski, T., Kazon, M., Borkowski, A., Witeska, A., and Kuczera, J. Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses. Clin Ther 1993;15(6):1011-1020.
  • Kulze, A. and Greaves, M. Contact urticaria caused by stinging nettles. Br.J Dermatol. 1988;119(2):269-270.
  • Lichius J. J., Muth C. The inhibiting effects of Urtica dioica root extracts on experimentally induced prostatic hyperplasia in the mouse. Planta Med 1997;63:307-10.
  • Lichius, J. J., Lenz, C., Lindemann, P., Muller, H. H., Aumuller, G., and Konrad, L. Antiproliferative effect of a polysaccharide fraction of a 20% methanolic extract of stinging nettle roots upon epithelial cells of the human prostate (LNCaP). Pharmazie 1999;54(10):768-771.
  • Lopatkin N, Sivkov A, Walther C, et al. Long-term efficacy and safety of a combination of sabal and urtica extract for lower urinary tract symptoms–a placebo-controlled, double-blind, multicenter trial. World J Urol 2005;23:139-46.
  • Lopatkin, N. A., Sivkov, A. V., Medvedev, A. A., Walter, K., Schlefke, S., Avdeichuk, IuI, Golubev, G. V., Mel’nik, K. P., Elenberger, N. A., and Engelman, U. [Combined extract of Sabal palm and nettle in the treatment of patients with lower urinary tract symptoms in double blind, placebo-controlled trial]. Urologiia. 2006;(2):12, 14-12, 19.
  • Lopatkin, N. A., Sivkov, A. V., Schlafke, S., Funk, P., Medvedev, A., and Engelmann, U. Efficacy and safety of a combination of Sabal and Urtica extract in lower urinary tract symptoms–long-term follow-up of a placebo-controlled, double-blind, multicenter trial. Int.Urol.Nephrol. 2007;39(4):1137-1146.
  • Luczaj, L. and Szymanski, W. M. Wild vascular plants gathered for consumption in the Polish countryside: a review. J.Ethnobiol.Ethnomed. 2007;3:17.
  • Maor D, Little M. Skin contact with a stinging tree requiring intensive care unit admission. Contact Dermatitis. 2017 Nov;77(5):335-37.
  • Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6.
  • Men C, Wang M, Aiyireti M, Cui Y. The efficacy and safety of Urtica dioica in treating benign prostatic hyperplasia: a systematic review and meta-analysis. Afr J Tradit Complement Alt Med 2016;13(2):143-50.
  • Mills S, Bone K. Principles and Practice of Phytotherapy. London: Churchill Livingstone, 2000.
  • Mittman P. Randomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis. Planta Med 1990;56:44-7.
  • More M, Gruenwald J, Pohl U, Uebelhack R. A Rosa canina – Urtica dioica – Harpagophytum procumbens/zeyheri combination significantly reduces gonarthritis symptoms in a randomized, placebo-controlled double-blind study. Planta Med. 2017 Dec;83(18):1384-91.
  • Najafipour F, Rahimi AO, Mobaseri M, Agamohamadzadeh N, Nikoo A, Aliasgharzadeh A. Therapeutic effects of stinging nettle (Urtica dioica) in women with hyperandrogenism. Int J Curr Res Aca Rev. 2014;2(7):153-160.
  • Namazi, N., Esfanjani, A. T., Heshmati, J., and Bahrami, A. The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial. Pak.J.Biol.Sci. 8-1-2011;14(15):775-779.
  • Obertreis, B., Ruttkowski, T., Teucher, T., Behnke, B., and Schmitz, H. Ex-vivo in-vitro inhibition of lipopolysaccharide stimulated tumor necrosis factor-alpha and interleukin-1 beta secretion in human whole blood by extractum urticae dioicae foliorum. Arzneimittelforschung 1996;46(4):389-394.
  • Oliver, F., Amon, E. U., Breathnach, A., Francis, D. M., Sarathchandra, P., Black, A. K., and Greaves, M. W. Contact urticaria due to the common stinging nettle (Urtica dioica)– histological, ultrastructural and pharmacological studies. Clin Exp Dermatol. 1991;16(1):1-7.
  • Onal S, Timur S, Okutucu B, Zihnioglu F. Inhibition of alpha-glucosidase by aqueous extracts of some potent antidiabetic medicinal herbs. Prep Biochem Biotechnol. 2005;35(1):29-36.
  • Patten G. Medicinal plant review: Urtica. Aust J Med Herbalism 1993;5(1):5-13.
  • Pavone, C., Abbadessa, D., Tarantino, M. L., Oxenius, I., Lagana, A., Lupo, A., and Rinella, M. [Associating Serenoa repens, Urtica dioica and Pinus pinaster. Safety and efficacy in the treatment of lower urinary tract symptoms. Prospective study on 320 patients]. Urologia. 2010;77(1):43-51.
  • Purnak, T., Ozaslan, E., Beyazit, Y., and Haznedaroglu, I. C. Upper gastrointestinal bleeding in a patient with defective hemostasis successfully treated with ankaferd blood stopper. Phytother.Res. 2011;25(2):312-313.
  • Randall C, Randall H, Dobbs F, et al. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain. J R Soc Med 2000;93:305-9.
  • Randall, C. F. Stinging nettles for osteoarthritis pain of the hip. Br.J Gen.Pract. 1994;44(388):533-534.
  • Randall, C., Dickens, A., White, A., Sanders, H., Fox, M., and Campbell, J. Nettle sting for chronic knee pain: a randomised controlled pilot study. Complement Ther.Med. 2008;16(2):66-72.
  • Randall, C., Meethan, K., Randall, H., and Dobbs, F. Nettle sting of Urtica dioica for joint pain–an exploratory study of this complementary therapy. Complement Ther Med 1999;7(3):126-131.
  • Rau O, Wurglics M, Dingermann T, Abdel-Tawab M, Schubert-Zsilavecz M. Screening of herbal extracts for activation of the human peroxisome proliferator-activated receptor. Pharmazie. 2006;61(11):952-6.
  • Rayburn, K., Fleischbein, E., Song, J., Allen, B., Kundert, M., Leiter, C., and Bush, T. Stinging nettle cream for osteoarthritis. Altern.Ther.Health Med. 2009;15(4):60-61.
  • Rhodes, L., Primka, R. L., Berman, C., Vergult, G., Gabriel, M., Pierre-Malice, M., and Gibelin, B. Comparison of finasteride (Proscar), a 5 alpha reductase inhibitor, and various commercial plant extracts in in vitro and in vivo 5 alpha reductase inhibition. Prostate 1993;22(1):43-51.
  • Riehemann, K., Behnke, B., and Schulze-Osthoff, K. Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the proinflammatory transcription factor NF-kB. FEBS Lett 1-8-1999;442(1):89-94.
  • Safarinejad, M. R. Urtica dioica for treatment of benign prostatic hyperplasia: a prospective, randomized, double-blind, placebo-controlled, crossover study. J.Herb.Pharmacother. 2005;5(4):1-11.
  • Sahin, M., Yilmaz, H., Gursoy, A., Demirel, A. N., Tutuncu, N. B., and Guvener, N. D. Gynaecomastia in a man and hyperoestrogenism in a woman due to ingestion of nettle (Urtica dioica). N.Z.Med.J. 2007;120(1265):U2803.
  • Schneider H, Honold E, and Masuhr T. Treatment of benign prostatic hyperplasia with a combination plant preparation. Results of an observational study of sabal extract WS 1473 and Urtica extract WS 1031 in the offices of urologists. Fortschr Med 1995;113(3):37-40.
  • Schneider, T. and Rubben, H. [Stinging nettle root extract (Bazoton-uno) in long term treatment of benign prostatic syndrome (BPS). Results of a randomized, double-blind, placebo controlled multicenter study after 12 months]. Urologe A 2004;43(3):302-306.
  • Schottner M, Gansser D, Spiteller G, et al. Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG). Planta Med 1997;63:529-32.
  • Schöttner M, Spiteller G, Gansser D. Lignans Interfering with 5alpha-dihydrotestosterone binding to human sex hormone-binding globulin. J Nat Prod. 1998;61(1):119-21.
  • Simões-Pires CA, Hmicha B, Marston A, Hostettmann K. A TLC bioautographic method for the detection of alpha- and beta-glucosidase inhibitors in plant extracts. Phytochem Anal. 2009;20(6):511-5.
  • Sokeland J, Albrecht J. [Combination of Sabal and Urtica extract vs. finasteride in benign prostatic hyperplasia (Aiken stages I to II). Comparison of therapeutic effectiveness in a one year double-blind study]. Urologe A 1997;36:327-33.
  • Sokeland J. Combined sabal and urtica extract compared with finasteride in men with benign prostatic hyperplasia: analysis of prostate volume and therapeutic outcome. BJU Int 2000;86:439-42.
  • Tabrizi R, Sekhavati E, Nowrouzi-Sohrabi P, et al. Effects of Urtica dioica on Metabolic Profiles in Type 2 Diabetes: A Systematic Review and Meta-analysis of Clinical Trials. Mini Rev Med Chem 2022;22(3):550-563.
  • Tahri, A., Yamani, S., Legssyer, A., Aziz, M., Mekhfi, H., Bnouham, M., and Ziyyat, A. Acute diuretic, natriuretic and hypotensive effects of a continuous perfusion of aqueous extract of Urtica dioica in the rat. J Ethnopharmacol 2000;73(1-2):95-100.
  • Van der Weijden, G. A., Timmer, C. J., Timmerman, M. F., Reijerse, E., Mantel, M. S., and van, der, V. The effect of herbal extracts in an experimental mouthrinse on established plaque and gingivitis. J Clin Periodontol. 1998;25(5):399-403.
  • Van Parijs J, Broekaert WF, and Peumans WJ. Urtica dioica agglutinin: a plant lectin with antifungal properties. Archives Internationales de Physiologie et de Biochimie 1988;96(1):31.
  • Vontobel HP, Herzog R, Rutishauser G, Kres H. [Results of a double-blind study on the effectiveness of ERU (extractum radicis Urticae) capsules in conservative treatment of benign prostatic hyperplasia]. (Abstract). Urologe A 1985;24:49-51.
  • Wagner H, Geiger WN, Boos G, and et al. Studies on the binding of Urtica dioica agglutinin (UDA) and other lectins in an in vitro epidermal growth factor receptor test. Phytomedicine 1995;4:287-290.
  • Wagner H, Willer F, Samtleben R, and et al. Search for the antiprostatic principle of stinging nettle (Urtica dioica) roots. Phytomedicine 1994;1:213-224.
  • Younger J, Donovan EK, Hodgin KS, Ness TJ. A placebo-controlled, pseudo-randomized, crossover trial of botanical agents for Gulf war illness: Reishi mushroom (Ganoderma lucidum), stinging nettle (Urtica dioica), and Epimedium (Epimedium sagittatum). Int J Environ Res Public Health 2021;18(7):3671.
  • Ziaei R, Foshati S, Hadi A, et al. The effect of nettle (Urtica dioica) supplementation on the glycemic control of patients with type 2 diabetes mellitus: a systematic review and meta-analysis. Phytother Res 2020;34(2):282-94.

Rosehips

  • Basim, E. and Basim, H. Antibacterial activity of Rosa damascena essential oil. Fitoterapia 2003;74(4):394-396.
  • Biswas, N. R., Gupta, S. K., Das, G. K., Kumar, N., Mongre, P. K., Haldar, D., and Beri, S. Evaluation of Ophthacare eye drops–a herbal formulation in the management of various ophthalmic disorders. Phytother.Res. 2001;15(7):618-620.
  • Cho, E. J., Yokozawa, T., Rhyu, D. Y., Kim, S. C., Shibahara, N., and Park, J. C. Study on the inhibitory effects of Korean medicinal plants and their main compounds on the 1,1-diphenyl-2-picrylhydrazyl radical. Phytomedicine. 2003;10(6-7):544-551.
  • Chrubasik, C., Duke, R. K., and Chrubasik, S. The evidence for clinical efficacy of rose hip and seed: a systematic review. Phytother Res 2006;20(1):1-3.
  • Daels-Rakotoarison, D. A., Gressier, B., Trotin, F., Brunet, C., Luyckx, M., Dine, T., Bailleul, F., Cazin, M., and Cazin, J. C. Effects of Rosa canina fruit extract on neutrophil respiratory burst. Phytother.Res. 2002;16(2):157-161.
  • Dushkin, M. I., Zykov, A. A., and Pivovarova, E. N. [The effect of natural polyphenol compounds on the oxidative modification of low-density lipoproteins]. Biull.Eksp.Biol Med 1993;116(10):393-395.
  • Hornero-Mendez, D. and Minguez-Mosquera, M. I. Carotenoid pigments in Rosa mosqueta hips, an alternative carotenoid source for foods. J Agric Food Chem 2000;48(3):825-828.
  • Janse, van Rensburg, Erasmus, E., Loots, D. T., Oosthuizen, W., Jerling, J. C., Kruger, H. S., Louw, R., Brits, M., and van der Westhuizen, F. H. Rosa roxburghii supplementation in a controlled feeding study increases plasma antioxidant capacity and glutathione redox state. Eur J Nutr 2005;44(7):452-457.
  • Kumarasamy, Y., Cox, P. J., Jaspars, M., Nahar, L., and Sarker, S. D. Screening seeds of Scottish plants for antibacterial activity. J Ethnopharmacol 2002;83(1-2):73-77.
  • Larsen, E., Kharazmi, A., Christensen, L. P., and Christensen, S. B. An antiinflammatory galactolipid from rose hip (Rosa canina) that inhibits chemotaxis of human peripheral blood neutrophils in vitro. J.Nat.Prod. 2003;66(7):994-995.
  • Ma, Y. X., Zhu, Y., Wang, C. F., Wang, Z. S., Chen, S. Y., Shen, M. H., Gan, J. M., Zhang, J. G., Gu, Q., and He, L. The aging retarding effect of ‘Long-Life CiLi’. Mech.Ageing Dev 1997;96(1-3):171-180.
  • Moreno Gimenez, J. C., Bueno, J., Navas, J., and Camacho, F. [Treatment of skin ulcer using oil of mosqueta rose]. Med Cutan.Ibero.Lat.Am 1990;18(1):63-66.
  • Rein, E., Kharazmi, A., and Winther, K. A herbal remedy, Hyben Vital (stand. powder of a subspecies of Rosa canina fruits), reduces pain and improves general wellbeing in patients with osteoarthritis–a double-blind, placebo-controlled, randomised trial. Phytomedicine. 2004;11(5):383-391.
  • Rein, E., Kharazmi, A., Thamsborg, G., and Winther, K. Herbal remedy made from a subspecies of rose-hip Rosa canina reduces symptoms of knee and hip osteoarthritis. Osteoarthr Cartil 2004;12(Suppl 2):80.
  • Rossnagel, K. and Willich, S. N. [Value of complementary medicine exemplified by rose-hips]. Gesundheitswesen 2001;63(6):412-416.
  • Shabykin, G. P. and Godorazhi, A. I. [A polyvitamin preparation of fat-soluble vitamins (carotolin) and rose hip oil in the treatment of certain dermatoses]. Vestn.Dermatol.Venerol. 1967;41(4):71-73.
  • Shiota, S., Shimizu, M., Mizusima, T., Ito, H., Hatano, T., Yoshida, T., and Tsuchiya, T. Restoration of effectiveness of beta-lactams on methicillin-resistant Staphylococcus aureus by tellimagrandin I from rose red. FEMS Microbiol.Lett 4-15-2000;185(2):135-138.
  • Teng, C. M., Kang, Y. F., Chang, Y. L., Ko, F. N., Yang, S. C., and Hsu, F. L. ADP-mimicking platelet aggregation caused by rugosin E, an ellagitannin isolated from Rosa rugosa Thunb. Thromb.Haemost. 1997;77(3):555-561.
  • Trovato, A., Monforte, M. T., Forestieri, A. M., and Pizzimenti, F. In vitro anti-mycotic activity of some medicinal plants containing flavonoids. Boll Chim Farm 2000;139(5):225-227.
  • Venkatesh, R. P., Ramaesh, K., and Browne, B. Rose-hip keratitis. Eye 2005;19(5):595-596.
  • Warholm, O., Skaar, S., Hedman, E., Molmen, H. M., and Eik, L. The effects of a standardized herbal remedy ade from a subtype of Rosa canina in patients with osteoarthritis: a double-blind, randomized, placebo-controlled clinical trial. Curr Ther Res 2003;64(1):21-31.
  • Winther, K. and Kharazmi, A. A powder prepared from seeds and shells of subtype of rose-hip Rosa canina reduces pain in patients with osteoarthritis of the hand – a double blind, placebo-controlled study. Osteoarthr Cartil 2004;12(Suppl 2):145.
  • Winther, K., Apel, K., and Thamsborg, G. A powder made from seeds and shells of a rose-hip subspecies (Rosa canina) reduces symptoms of knee and hip osteoarthritis: a randomized, double-blind, placebo-controlled clinical trial. Scand J Rheumatol. 2005;34(4):302-308.
  • Andersson U, Berger K, Hogberg A, et al. Effects of rose hip intake on risk markers of type 2 diabetes and cardiovascular disease: a randomized, double-blind, cross-over investigation in obese persons. Eur J Clin Nutr 2012;66:585-90.
  • Back D. J., Breckenridge A. M., MacIver M, et al. Interaction of ethinyloestradiol with ascorbic acid in man. Br Med J (Clin Res Ed) 1981;282:1516.
  • Bani S, Hasanpour S, Mousavi Z, Mostafa Garehbaghi P, Gojazadeh M. The effect of Rosa damascena extract on primary dysmenorrhea: A double-blind cross-over clinical trial. Iran Red Crescent Med J. 2014;16(1):e14643.
  • Bottari A, Belcaro G, Ledda A, et al. Lady Prelox improves sexual function in generally healthy women of reproductive age. Minerva Ginecol 2013;65(4):435-44.
  • Cesarone MR, Belcaro G, Scipione C, et al. Prevention of vaginal dryness in perimenopausal women. Supplementation with Lady Prelox®. Minerva Ginecol. 2019;71(6):434-41.
  • Conklin KA. Cancer chemotherapy and antioxidants. J Nutr 2004;134:3201S-3204S.
  • Electronic Code of Federal Regulations. Title 21. Part 182 — Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  • Feetam CL, Leach RH, Meynell MJ. Lack of a clinically important interaction between warfarin and ascorbic acid. Toxicol Appl Pharmacol 1975;31:544-7.
  • Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
  • Fresz T, Nagy E, Hilbert A, Tomcsanyi J. The role of flavonoids in false positive digoxin assays caused by the consumption of hibiscus flower and rose hip tea. Int J Cardiol 2014;171(2):273-4.
  • García Hernández JÁ, Madera González D, Padilla Castillo M, Figueras Falcón T. Use of a specific anti-stretch mark cream for preventing or reducing the severity of striae gravidarum. Randomized, double-blind, controlled trial. Int J Cosmet Sci. 2013;35(3):233-7.
  • Han SH, Hur MH, Buckle J, et al. Effect of aromatherapy on symptoms of dysmenorrhea in college students: A randomized placebo-controlled clinical trial. J Altern Complement Med 2006;12(6):535-41.
  • Hansten P. D., Hayton W. L. Effect of antacid and ascorbic acid on serum salicylate concentration. J Clin Pharmacol 1980;20:326-31.
  • Hansten P. D., Horn J. R. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  • Hume R, Johnstone JM, Weyers E. Interaction of ascorbic acid and warfarin. JAMA 1972;219:1479.
  • Jiang K, Tang K, Liu H, Xu H, Ye Z, Chen Z. Ascorbic acid supplements and kidney stones incidence among men and women: a systematic review and meta-analysis. Urol J. 2019;16(2):115-120.
  • Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology 1999;13:1003-8.
  • Levine M, Rumsey SC, Daruwala R, et al. Criteria and recommendations for vitamin C intake. JAMA 1999;281:1415-23.
  • Mármol I, Sánchez-de-Diego C, Jiménez-Moreno N, Ancín-Azpilicueta C, Rodríguez-Yoldi MJ. Therapeutic applications of rose hips from different Rosa species. Int J Mol Sci. 2017;18(6):1137.
  • McLeod DC, Nahata MC. Inefficacy of ascorbic acid as a urinary acidifier (letter). N Engl J Med 1977;296:1413.
  • Moré M, Gruenwald J, Pohl U, Uebelhack R. A Rosa canina – urtica dioica – harpagophytum procumbens/zeyheri combination significantly reduces gonarthritis symptoms in a randomized, placebo-controlled double-blind study. Planta Med 2017;83(18):1384-91.
  • Morris JC, Beeley L, Ballantine N. Interaction of ethinyloestradiol with ascorbic acid in man [letter]. Br Med J (Clin Res Ed) 1981;283:503.
  • Mostafa-Gharabaghi P, Delazar A, Gharabaghi MM, Shobeiri MJ, Khaki A. The view of cesarean pain after preemptive use of Rosa damascena extract in women with elective cesarean section. World Sci J. 2013;4:226-35.
  • Oprica L, Bucsa C, Zamfiranche MM. Ascorbic acid content of rose hip fruit depending on altitude. Iran J Public Health 2015;44(1):138-9.
  • Parandin R, Ghowsi M, Dadbod A. Protective effects of hydroalcoholic extract of Rosa canina L. fruit on cyclophosphamide-induced testicular toxicity in mice. Avicenna J Phytomed 2023;13(1):7-17.
  • Phetcharat L, Wongsuphasawat K, Winther K. The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity. Clin Interv Aging. 2015;10:1849-56.
  • Prasad KN. Rationale for using high-dose multiple dietary antioxidants as an adjunct to radiation therapy and chemotherapy. J Nutr 2004;134:3182S-3S.
  • Rosenthal G. Interaction of ascorbic acid and warfarin. JAMA 1971;215:1671.
  • Seifi M, Abbasalizadeh S, Mohammad-Alizadeh-Charandabi S, Khodaie L, Mirghafourvand M. The effect of Rosa (L. Rosa canina) on the incidence of urinary tract infection in the puerperium: a randomized placebo-controlled trial. Phytother Res 2018;32(1):76-83.
  • Smith EC, Skalski RJ, Johnson GC, Rossi GV. Interaction of ascorbic acid and warfarin. JAMA 1972;221:1166.
  • Taylor EN, Stampfer MJ, Curhan GC. Dietary factors and the risk of incident kidney stones in men: new insights after 14 years of follow-up. J Am Soc Nephrol 2004;15:3225-32.
  • Traxer O, Huet B, Poindexter J, et al. Effect of ascorbic acid consumption on urinary stone risk factors. J Urol 2003;170:397-401.
  • Van Steirteghem AC, Robertson EA, Young DS. Influence of large doses of ascorbic acid on laboratory test results. Clin Chem. 1978;24(1):54-7.
  • Vihtamaki T, Parantainen J, Koivisto AM, et al. Oral ascorbic acid increases plasma oestradiol during postmenopausal hormone replacement therapy. Maturitas 2002;42:129-35.
  • Weintraub M, Griner PF. Warfarin and ascorbic acid: lack of evidence for a drug interaction. Toxicol Appl Pharmacol 1974;28:53-6.
  • Willich SN, Rossnagel K, Roll S, et al. Rose hip herbal remedy in patients wth rheumatoid arthritis – a randomised controlled trial. Phytomedicine 2010;17:87-93.
  • Young DS. Effects of Drugs on Clinical Laboratory Tests 4th ed. Washington: AACC Press, 1995.

Spearmint

  • Abe, S., Maruyama, N., Hayama, K., Inouye, S., Oshima, H., and Yamaguchi, H. Suppression of neutrophil recruitment in mice by geranium essential oil. Mediators.Inflamm. 2004;13(1):21-24.
  • Abe, S., Maruyama, N., Hayama, K., Ishibashi, H., Inoue, S., Oshima, H., and Yamaguchi, H. Suppression of tumor necrosis factor-alpha-induced neutrophil adherence responses by essential oils. Mediators.Inflamm. 2003;12(6):323-328.
  • Akdogan, M., Kilinc, I., Oncu, M., Karaoz, E., and Delibas, N. Investigation of biochemical and histopathological effects of Mentha piperita L. and Mentha spicata L. on kidney tissue in rats. Hum.Exp Toxicol. 2003;22(4):213-219.
  • Akdogan, M., Tamer, M. N., Cure, E., Cure, M. C., Koroglu, B. K., and Delibas, N. Effect of spearmint (Mentha spicata Labiatae) teas on androgen levels in women with hirsutism. Phytother.Res 2007;21(5):444-447.
  • Andersen, K. E. Contact allergy to toothpaste flavors. Contact Dermatitis 1978;4(4):195-198.
  • Arumugam, P. Priya N. Subathra M. Ramesh A. Environmental Toxicology & Pharmacology 2008;26(1):92-95.
  • Baker, J. R., Bezance, J. B., Zellaby, E., and Aggleton, J. P. Chewing gum can produce context-dependent effects upon memory. Appetite 2004;43(2):207-210.
  • Bonamonte, D., Mundo, L., Daddabbo, M., and Foti, C. Allergic contact dermatitis from Mentha spicata (spearmint). Contact Dermatitis 2001;45(5):298.
  • Bulat, R., Fachnie, E., Chauhan, U., Chen, Y., and Tougas, G. Lack of effect of spearmint on lower oesophageal sphincter function and acid reflux in healthy volunteers. Aliment.Pharmacol Ther. 1999;13(6):805-812.
  • Clayton, R. and Orton, D. Contact allergy to spearmint oil in a patient with oral lichen planus. Contact Dermatitis 2004;51(5-6):314-315.
  • Dal Sacco, D., Gibelli, D., and Gallo, R. Contact allergy in the burning mouth syndrome: a retrospective study on 38 patients. Acta Derm.Venereol. 2005;85(1):63-64.
  • de Sousa, D. P., Farias Nobrega, F. F., and de Almeida, R. N. Influence of the chirality of (R)-(-)- and (S)-(+)-carvone in the central nervous system: a comparative study. Chirality 5-5-2007;19(4):264-268.
  • Francalanci, S., Sertoli, A., Giorgini, S., Pigatto, P., Santucci, B., and Valsecchi, R. Multicentre study of allergic contact cheilitis from toothpastes. Contact Dermatitis 2000;43(4):216-222.
  • Goncalves, J. C., Oliveira, Fde S., Benedito, R. B., de Sousa, D. P., de Almeida, R. N., and de Araujo, D. A. Antinociceptive activity of (-)-carvone: evidence of association with decreased peripheral nerve excitability. Biol Pharm Bull. 2008;31(5):1017-1020.
  • Grant, P. Spearmint herbal tea has significant anti-androgen effects in polycystic ovarian syndrome. A randomized controlled trial. Phytother.Res 2010;24(2):186-188.
  • Guney, M., Oral, B., Karahanli, N., Mungan, T., and Akdogan, M. The effect of Mentha spicata Labiatae on uterine tissue in rats. Toxicol.Ind.Health 2006;22(8):343-348.
  • Imai, H., Osawa, K., Yasuda, H., Hamashima, H., Arai, T., and Sasatsu, M. Inhibition by the essential oils of peppermint and spearmint of the growth of pathogenic bacteria. Microbios 2001;106 Suppl 1:31-39.
  • Johnson, A. J. and Miles, C. Chewing gum and context-dependent memory: the independent roles of chewing gum and mint flavour. Br.J Psychol. 2008;99(Pt 2):293-306.
  • Johnson, A. J. and Miles, C. Evidence against memorial facilitation and context-dependent memory effects through the chewing of gum. Appetite 2007;48(3):394-396.
  • Kumar, V., Kural, M. R., Pereira, B. M., and Roy, P. Spearmint induced hypothalamic oxidative stress and testicular anti-androgenicity in male rats – altered levels of gene expression, enzymes and hormones. Food Chem Toxicol. 2008;46(12):3563-3570.
  • Larsen, W., Nakayama, H., Fischer, T., Elsner, P., Frosch, P., Burrows, D., Jordan, W., Shaw, S., Wilkinson, J., Marks, J., Jr., Sugawara, M., Nethercott, M., and Nethercott, J. Fragrance contact dermatitis: a worldwide multicenter investigation (Part II). Contact Dermatitis 2001;44(6):344-346.
  • Masumoto, Y., Morinushi, T., Kawasaki, H., Ogura, T., and Takigawa, M. Effects of three principal constituents in chewing gum on electroencephalographic activity. Psychiatry Clin.Neurosci. 1999;53(1):17-23.
  • Miles, C. and Johnson, A. J. Chewing gum and context-dependent memory effects: a re-examination. Appetite 2007;48(2):154-158.
  • Ormerod, A. D. and Main, R. A. Sensitisation to “sensitive teeth” toothpaste. Contact Dermatitis 1985;13(3):192-193.
  • Poon, T. S. and Freeman, S. Cheilitis caused by contact allergy to anethole in spearmint flavoured toothpaste. Australas.J Dermatol. 2006;47(4):300-301.
  • Pratap, S, Mithravinda, Mohan, YS, Rajoshi, C, and Reddy, PM. Antimicrobial activity and bioautography of essential oils from selected Indian medicinal plants (MAPS-P-410). International Pharmaceutical Federation World Congress 2002;62:133.
  • Rafii, F. and Shahverdi, A. R. Comparison of essential oils from three plants for enhancement of antimicrobial activity of nitrofurantoin against enterobacteria. Chemotherapy 2007;53(1):21-25.
  • Rasooli, I., Shayegh, S., and Astaneh, S. The effect of Mentha spicata and Eucalyptus camaldulensis essential oils on dental biofilm. Int J Dent.Hyg. 2009;7(3):196-203.
  • Skrebova, N., Brocks, K., and Karlsmark, T. Allergic contact cheilitis from spearmint oil. Contact Dermatitis 1998;39(1):35.
  • Sokovic, M. D., Vukojevic, J., Marin, P. D., Brkic, D. D., Vajs, V., and van Griensven, L. J. Chemical composition of essential oils of Thymus and Mentha species and their antifungal activities. Molecules. 2009;14(1):238-249.
  • Soliman, K. M. and Badeaa, R. I. Effect of oil extracted from some medicinal plants on different mycotoxigenic fungi. Food Chem.Toxicol 2002;40(11):1669-1675.
  • Tomson, N., Murdoch, S., and Finch, T. M. The dangers of making mint sauce. Contact Dermatitis 2004;51(2):92-93.
  • Torney, L. K., Johnson, A. J., and Miles, C. Chewing gum and impasse-induced self-reported stress. Appetite 2009;53(3):414-417.
  • Tucha, O., Mecklinger, L., Maier, K., Hammerl, M., and Lange, K. W. Chewing gum differentially affects aspects of attention in healthy subjects. Appetite 2004;42(3):327-329.
  • Wilkinson, L., Scholey, A., and Wesnes, K. Chewing gum selectively improves aspects of memory in healthy volunteers. Appetite 2002;38(3):235-236.
  • Yu, T. W., Xu, M., and Dashwood, R. H. Antimutagenic activity of spearmint. Environ Mol.Mutagen. 2004;44(5):387-393.
  • Zhao, C. Z., Wang, Y., Tang, F. D., Zhao, X. J., Xu, Q. P., Xia, J. F., and Zhu, Y. F. [Effect of Spearmint oil on inflammation, oxidative alteration and Nrf2 expression in lung tissue of COPD rats]. Zhejiang.Da.Xue.Xue.Bao.Yi.Xue.Ban. 2008;37(4):357-363.
  • Akdogan M, Ozguner M, Aydin G, Gokalp O. Investigation of biochemical and histopathological effects of Mentha piperita Labiatae and Mentha spicata Labiatae on liver tissue in rats. Hum Exp Toxicol 2004;23:21-8.
  • Akdogan M, Ozguner M, Kocak A, et al. Effects of peppermint teas on plasma testosterone, follicle-stimulating hormone, and luteinizing hormone levels and testicular tissue in rats. Urology 2004;64:394-8.
  • Bardaweel SK, Bakchiche B, ALSalamat HA, Rezzoug M, Gherib A, Flamini G. Chemical composition, antioxidant, antimicrobial and antiproliferative activities of essential oil of Mentha spicata L. (Lamiaceae) from Algerian Saharan atlas. BMC Complement Altern Med. 2018;18(1):201.
  • Connelly AE, Tucker AJ, Tulk H, et al. High-rosmarinic acid spearmint tea in the management of knee osteoarthritis symptoms. J Med Food 2014;17:1361-7.
  • Damiani E, Aloia AM, Priore MG, et al. Allergy to mint (Mentha spicata). J Investig Allergol Clin Immunol 2012;22:309-10.
  • Electronic Code of Federal Regulations. Title 21. Part 182 — Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  • Falcone PH, Nieman KM, Tribby AC, et al. The attention-enhancing effects of spearmint extract supplementation in healthy men and women: a randomized, double-blind, placebo-controlled, parallel trial. Nutr Res. 2019;64:24-38.
  • Falcone PH, Tribby AC, Vogel RM, et al. Efficacy of a nootropic spearmint extract on reactive agility: a randomized, double-blind, placebo-controlled, parallel trial. J Int Soc Sports Nutr. 2018;15(1):58.
  • Gunatheesan S, Tam MM, Tate B, et al. Retrospective study of oral lichen planus and allergy to spearmint oil. Australas J Dermatol 2012;53:224-8.
  • Herrlinger KA, Nieman KM, Sanoshy KD, et al. Spearmint extract improves working memory in men and women with age-associated memory impairment. J Altern Complement Med. 2018;24(1):37-47.
  • Hunt R, Dienemann J, Norton HJ, Hartley W, Hudgens A, Stern T, Divine G. Aromatherapy as treatment for postoperative nausea: a randomized trial. Anesth Analg 2013;117(3):597-604.
  • Lasrado JA, Nieman KM, Fonseca BA, et al. Safety and tolerability of a dried aqueous spearmint extract. Regul Toxicol Pharmacol 2017;86:167-176.
  • Vejdani R, Shalmani HR, Mir-Fattahi M, et al. The efficacy of an herbal medicine, Carmint, on the relief of abdominal pain and bloating in patients with irritable bowel syndrome: a pilot study. Dig Dis Sci. 2006 Aug;51:1501-7.

Conditions Of Use And Important Information

This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on our website. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

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